Showing 1 - 10 of 17 Items
Role of Polycomb group proteins in regulation of eyes absent gene expression in Drosophila melanogaster This record is embargoed.
- Embargo End Date: 2027-05-16
Date: 2024-01-01
Creator: Joanne Du
Access: Embargoed
Determining the influence of proximal Zeste binding sites and promoters on rates of transvection This record is embargoed.
- Embargo End Date: 2026-05-17
Date: 2023-01-01
Creator: Molly Henderson
Access: Embargoed
Investigating the Role of Helicobacter pylori Glycan Biosynthesis in Modulating Host Immune Cell Recognition Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2023-01-01
Creator: Katharine Barrett
Access: Access restricted to the Bowdoin Community
Live imaging of somatic homolog pairing in Drosophila supports a button-based mechanism for pairing facilitated by the genetic insulator gypsy This record is embargoed.
- Embargo End Date: 2026-05-18
Date: 2023-01-01
Creator: Holden D. Hadfield
Access: Embargoed
Characterization of Spaetzle-Toll Ligand-Receptor Pairs in Gryllus bimaculatus Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2028-06-01
Date: 2023-01-01
Creator: Tabarak Al Musawi
Access: Access restricted to the Bowdoin Community
Enhancer usage variation assessed via chromatin-conformation within and among three species of Drosophila This record is embargoed.
- Embargo End Date: 2027-05-19
Date: 2022-01-01
Creator: Maia B. Granoski
Access: Embargoed
Genetic Analysis of Adhesion Protein ELMO3 in Arabidopsis thaliana
Date: 2022-01-01
Creator: Garrison Asper
Access: Open access
- The Extracellular Matrix (ECM) between plant cells is vital for structure, development, and intercellular adhesion. A pectin rich layer in between cells, the middle lamella, is largely responsible for regulating the adhesive properties of adjacent plant cells. Homogalacturonan (HG) pectin, the most common, is synthesized in the Golgi and secreted into the ECM where it undergoes calcium crosslinking, increasing its adhesive properties. Mutations in proteins essential for HG synthesis can reveal a severe adhesion defective phenotype, where the hypocotyls of dark grown Arabidopsis exhibit cell sloughing, curling, and general disorganization. A family of five ELMO proteins are suspected to act as scaffolds for pectin biosynthesis enzymes. ELMO1 and ELMO4 mutants exhibit an adhesion deficient phenotype, and a double mutant provides evidence of redundancy in function between ELMO1 and ELMO2. ELMO1-GFP co-immunoprecipitated with enzymes required for HG synthesis indicating its role as a scaffold protein. Double mutants of the other ELMO homologues were created to determine if they exhibit functional redundancy, and ELMO1 and ELMO3 appear partially redundant. A gene deletion of ELMO3 was also created using the CRSPR/Cas9 system, resulting in two distinct elmo3 deletion alleles, which were phenotypically identical to the original elmo3-/- mutant. All adhesion defective phenotypes can be partially suppressed by altering the osmoticum and hence turgor that provides pressure on adhesive cells. Lastly, ELMO3-GFP was localized to the Golgi, the site of pectin biosynthesis, further supporting a common role of the ELMOs in pectin biosynthesis.
Bacterial Coat of Armor: Probing how Glycan Biosynthesis in Helicobacter pylori Modulates Host Immune Recognition Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2022-01-01
Creator: Francis Jacob Kassama
Access: Access restricted to the Bowdoin Community
Testing conservation of an mRNA transport pathway in yeast Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2021-01-01
Creator: Kyu Young "Kevin" Chi
Access: Access restricted to the Bowdoin Community
Regulation of eyes absent gene expression in Drosophila melanogaster by Polycomb Group Response Elements Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2025-06-01
Date: 2020-01-01
Creator: Boris S. Dimitrov
Access: Access restricted to the Bowdoin Community