Showing 1 - 10 of 10 Items
The effects of manipulated afterload pressure on heartbeat frequency, active force, and cardiac output of the American lobster, Homarus americanus Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2019-05-01
Creator: Gina Fickera
Access: Access restricted to the Bowdoin Community
Sex- and age-specific susceptibility of parvalbumin neurons to DNA methylation in a model of early life adversity This record is embargoed.
- Embargo End Date: 2025-05-19
Date: 2022-01-01
Creator: Alissa Chen
Access: Embargoed
Non-genomic effects of steroids on teleost fish olfaction: behavioral and anatomical approaches Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2020-01-01
Creator: Leah B Kratochvil
Access: Access restricted to the Bowdoin Community
Exploring sex-specific and developmental outcomes of early life adversity on DNA methylation in parvalbumin-containing interneurons Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2023-01-01
Creator: Emma Straw Noel
Access: Access restricted to the Bowdoin Community
Context-specific effects of vasotocin on social approach in the male common goldfish, Carassius auratus
Date: 2019-05-01
Creator: Katharine Torrey
Access: Open access
- The peptide vasotocin (VT) and its mammalian homologue, vasopressin (VP), produce effects on social behavior that are highly species- and context-specific. We recently sequenced two genes for V1a-like receptors (VTR) in the goldfish brain, one that encodes for a fully-functioning canonical receptor and one that encodes for a non-functional truncated receptor. The current study is an investigation of whether social context may alter expression of these receptor types and thus, potentially, behavioral responses to VT. We used western blotting and immunohistochemistry with custom anti-VTR antibodies to characterize the distribution of VTR throughout the forebrain and the hindbrain. Western blot results showed bands close to the predicted sizes for truncated and canonical VTR constructs, suggesting that both genes are translated into protein in the brain, but the presence of additional bands suggested potential nonspecific binding. Immunohistochemistry data revealed VTR signal throughout the brain in regions associated with social behavior. We additionally examined whether visual and olfactory context alters behavioral responsiveness to VT, potentially by altering the expression of one or both receptors. Behavioral tests suggested that VT inhibits approach to males, but its effect on response to females in reproductive contexts is still undetermined, likely due to interference from a stress response during testing. Further characterization of VTR throughout the brain will clarify how social context might alter VT signaling through context-dependent modulation of its receptors. Additionally, future work should examine the behavioral consequences of such modulation by further studying whether VT’s effect on social approach behavior depends on context.
The sex specific effects of acute ketamine treatment on parvalbumin and anxiety and depression following early life adversity Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2025-06-01
Date: 2022-01-01
Creator: Seneca N. Ellis
Access: Access restricted to the Bowdoin Community
Ultrasonic vocalization playback as an affective assay at both neural and behavioral levels: Implications for understanding adversity-induced emotional dysfunction Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2023-01-01
Creator: Sydney M Bonauto
Access: Access restricted to the Bowdoin Community
The role of pubertal hormones on female rats' sensitivity to acute ketamine treatment in an early-life-adversity model Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2024-01-01
Creator: Nuanxi (Sissi) Feng
Access: Access restricted to the Bowdoin Community
Early life adversity induces sex-specific behavioral changes and does not alter precocial neural recruitment in response to basolateral amygdala stimulation Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2024-01-01
Creator: Zackery D. Reynolds
Access: Access restricted to the Bowdoin Community
An unbiased glimpse into the sex-specific effects of ketamine treatment on rats who have experienced early life adversity. Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2023-01-01
Creator: Lucia Marie O'Sullivan
Access: Access restricted to the Bowdoin Community