Showing 841 - 850 of 2050 Items
Context-specific effects of vasotocin on social approach in the male common goldfish, Carassius auratus
Date: 2019-05-01
Creator: Katharine Torrey
Access: Open access
- The peptide vasotocin (VT) and its mammalian homologue, vasopressin (VP), produce effects on social behavior that are highly species- and context-specific. We recently sequenced two genes for V1a-like receptors (VTR) in the goldfish brain, one that encodes for a fully-functioning canonical receptor and one that encodes for a non-functional truncated receptor. The current study is an investigation of whether social context may alter expression of these receptor types and thus, potentially, behavioral responses to VT. We used western blotting and immunohistochemistry with custom anti-VTR antibodies to characterize the distribution of VTR throughout the forebrain and the hindbrain. Western blot results showed bands close to the predicted sizes for truncated and canonical VTR constructs, suggesting that both genes are translated into protein in the brain, but the presence of additional bands suggested potential nonspecific binding. Immunohistochemistry data revealed VTR signal throughout the brain in regions associated with social behavior. We additionally examined whether visual and olfactory context alters behavioral responsiveness to VT, potentially by altering the expression of one or both receptors. Behavioral tests suggested that VT inhibits approach to males, but its effect on response to females in reproductive contexts is still undetermined, likely due to interference from a stress response during testing. Further characterization of VTR throughout the brain will clarify how social context might alter VT signaling through context-dependent modulation of its receptors. Additionally, future work should examine the behavioral consequences of such modulation by further studying whether VT’s effect on social approach behavior depends on context.
Responses of central pattern generators in the American lobster STNS to multiple members of a novel neuropeptide family
Date: 2020-01-01
Creator: Benjamin Harley Wong
Access: Open access
- Neuropeptides are important modulators of neural activity, allowing neural networks, such as the central pattern generators (CPGs) that control rhythmic movements, to alter their output and thus generate behavioral flexibility. Isoforms of a neuropeptide family vary in physical structure, allowing potentially distinct functional neuromodulatory effects on CPG systems. While some familial neuropeptide isoforms can differentially affect a system, others in the same family may elicit indistinguishable effects. Here, we examined the effects elicited by members of a novel family of six peptide hormone isoforms (GSEFLamides: I-, M-, AL-, AM-, AV-, and VM-GSEFLamide) on the pyloric filter and gastric mill CPGs in the stomatogastric nervous system (STNS) of the American lobster, Homarus americanus. Recent unpublished work from the Dickinson lab found that five of the six GSEFLamides elicited similar increases in contraction amplitude when perfused through the isolated lobster heart, while one (AVGSEFLamide) had virtually no effect. Using extracellular recordings, we found the pattern of GSEFLamide effects on the STNS gastric mill to be similar to the pattern observed in the lobster cardiac system; the gastric mill circuit was fairly consistently activated by all isoforms except AVGSEFLamide. The intrinsically active pyloric pattern was also significantly enhanced by three out of five peptide isoforms, and nearly significantly enhanced by two more, but was likewise non-responsive to AVGSEFLamide. While the reason AVGSEFLamide had no effect on either pattern is unknown, the similar phenomenon noted in the isolated whole heart potentially indicates that this isoform lacks any function in the lobster.
Survival Strategies: Historic Preservation, Jewish Community, and the German Democratic Republic
Date: 2020-01-01
Creator: Emily Ann Cohen
Access: Open access
- Following the Second World War, as German Communists worked to establish a new socialist East German state, Jews who survived persecution and imprisonment by the Nazis worked to reestablish a Jewish community at the same time. Though many scholars dismiss the relationship between Jews and the Socialist Unity Party, the ruling party of the German Democratic Republic, as one characterized only by neglect and occasional political exploitation, it was much more nuanced, shaped in large part by the Cold War. Both the party and the Jewish community relied on the other to accomplish their goals, namely, survival in a new world order: The Socialist Unity Party relied on the Jewish community to maintain the German Democratic Republic's claim to legitimacy, and the Jews, few in number, relied on the party for financial support. Despite mutual benefits, however, the state and party nearly always had the upper hand. The power imbalance led Jews to find creative ways to fulfill their needs and, at several points, even prompted protest of the party’s treatment of its Jewish citizens. This paper follows the course of this relationship by focusing on the German Democratic Republic's management of sites of historical significance—which vacillated between outright destruction and dedicated protection—returning particularly to the Jewish cemetery in Berlin-Weissensee, one of the largest Jewish cemeteries in Europe. With this particular lens, this project addresses questions about memory, mythology, and agency in a socialist dictatorship and challenges assumptions about Jewish life in East Germany.
Duty and Distinction: Scientists as Intellectuals in Modern China
Date: 2020-01-01
Creator: Helen Wang
Access: Open access
- As critical players in the Chinese state’s pursuit of modernization and political legitimacy, Chinese scientists have been the recipients of state attention and scrutiny throughout modern history. This paper will analyze how Qian Xuesen (1911-2009) became a national hero as the Chinese Communist Party’s model scientist. Qian developed his scientific expertise in the United States, before Cold War political tensions forced his extradition. Upon his return to China, Qian became a key missile scientist in the state’s emerging nuclear weapons program. By analyzing Qian’s public persona as portrayed in official state media, this paper will argue that the CCP conferred distinct political duties to scientists, defining a new socio-political role for scientist-intellectuals. Beginning from the Mao era and continuing through to the present day, the CCP’s portrayal and promotion of Qian’s legacy gives insight into the state’s strategy to use science to bolster authority and legitimize policy.
The Impact of Armed Conflict on Maternal Health in Colombia
Date: 2020-01-01
Creator: Madeleine Squibb
Access: Open access
- This study combines data from the 2010 Demographic and Health Survey and the Conflict Analysis Resource Center (CERAC) to examine the impact of conflict on maternal health service utilization and outcomes in Colombia. The primary results indicate a significant, negative relationship between conflict level and antenatal and postnatal care utilization. Conflict is insignificant in determining the use of professional assistance at delivery. Although rural women are, overall, less likely to access maternal health services, further analysis along rural-urban lines reveals that the negative effect of violence on prenatal and postnatal care is stronger among urban women. Secondary estimation of the occurrence of complications during or after delivery employs a Two-Stage Residuals Inclusion model to address potential endogeneity in service use. Estimated results show that conflict levels are insignificant, but that Indigenous women and women in lower wealth quintiles are significantly more likely to experience complications, even after controlling for service use. The conclusions of this paper suggest that Colombia’s universal healthcare system has been successful in reducing economic barriers to prenatal care and professional delivery, but that significant wealth-related inequalities remain in maternal health outcomes. Additionally, Indigenous and women with lower levels of education are less likely to access services and more likely to experience complications. The primary contribution of this paper is the inclusion of a conflict measure. The significant, negative impact on prenatal and postnatal care utilization, especially for urban women, warrants further study to better inform policy to increase service use and reduce maternal mortality and morbidity.
“Bosques Si, Tala No”: The Uprising of Cherán K’eri
Date: 2020-01-01
Creator: Ray Tarango
Access: Open access
- In the spring of 2011, the indigenous community of Cherán K’eri in western Mexico rose up to protect their forests. Organized crime, and its allies, had taken over this town during the previous decade and had logged significant portions of its communal forests in the surrounding hills. This thesis examines the following questions: How do townspeople recall their experience under a narco state? What pushed this indigenous community to organize to protect the forest despite the threat of violence? What was it about this landscape in particular that brought people together? Previous research into this uprising has overlooked the gender dynamics of the community, and has failed to consider the townspeople’s connection to nature. Using interviews gathered over eighteen months in three separate visits, this thesis argues that despite patriarchal expectations that men “protect” the community and its resources it was women who led and organized the uprising. Chapter One analyzes how organized crime took control of the community, suggesting that memories and trauma of the “war on drugs” deeply affected the townspeople. Chapter Two centers on the uprising itself, exploring not only the gendered dynamics of that spring, but connecting the material and affective importance of the forest to the women who led the uprising. This thesis analyzes how organized crime took control of the community and argues that townspeople’s multilayered connection to nature played a central role in the town’s movement.
Perdido en la transculturación: Compromisos de identidad en la América Latina judía
Date: 2020-01-01
Creator: Jacob Bernard Baskes
Access: Open access
- Esta investigación explora los procesos de negociación y compromiso presentes en la experiencia judía de América Latina. Durante siglos, esta identidad ha existido junta con otras, sean nacionales, religiosas, o raciales, lo cual resulta en una nueva identidad compleja y singular. A través de novelas de Eduardo Halfon (Guatemala), Achy Obejas y Leonardo Padura (Cuba) e Isaac Goldemberg (Perú) en adición a una investigación antropológica en Lima, el texto explora una colección de temas que incluye el movimiento, la memoria, el exilio, la diáspora, el trauma, y el mestizaje. Cada tema aquí analizado tiene un rol profundo en la formación de la identidad judía de América Latina, tanto en su forma histórica como en su forma actual.
Political Polupragmones: Busybody Athenians, Meddlesome Citizenship, and Epistemic Democracy in Classical Athens
Date: 2016-01-01
Creator: Harry D Rube
Access: Open access
- The figure of the πολυπράγμων, the overactive, over-engaged, or meddlesome democratic citizen, is a literary trope that emerges in Classical Athenian literature in the 5th and 4th centuries B.C. This project seeks to use the πολυπράγμων as an entry point into understanding Athenian attitudes toward citizenship and socially acceptable political behaviors in Athens’ democratic era. I explore the history and usage of the term πολυπράγμων, and the associated characteristic of πολυπραγμοσύνη (meddlesomeness), and its synonyms and antecedents. I demonstrate that to be labeled πολυπράγμων is a term of social restraint—one is named a πολυπράγμων if they do not “mind their own business.” In 5th century Athens such an admonition is primarily political. It refers to and demonstrates the existence of a contested definition of what is and what is not acceptable political behavior on behalf of the non-elite citizens of Athens. Through a reading of Plato’s dialogues and an analysis of other Athenian literary productions describing street-level social and political interactions in the fourth century, I endeavor to demonstrate in the second half of this thesis that the behaviors of social inquisitiveness, over-activity, and the negative characteristics attributed to the πολυπράγμων by contemporary writers such as Plato, could actually have served to increase the common knowledge and cohesiveness of the Athenian city-state. To do this, I consider the πολυπράγμων through the lens of modern scholarship and social science that considers Athens as an “epistemic democracy” concerned with aggregating and employing politically useful information.
"I Remember!": Irish Postcolonial Memory in the Early Short Stories of Seán O'Faoláin
Date: 2023-01-01
Creator: Rebecca Norden-Bright
Access: Open access
- Seán O’Faoláin (1900-1991) was an Irish writer, cultural critic, and editor of the literary magazine The Bell. He wrote prolifically throughout the twentieth century, and while his short stories are often anthologized, much of his work is now out of print. This project will examine O’Faoláin’s first two short story collections, Midsummer Night Madness (1932) and A Purse of Coppers (1937), within the context of the post-independence period in Ireland. The 1930s is a period often glossed over in both political and literary histories of Ireland, overshadowed by the Literary Revival and primarily characterized by deepening conservatism and political strife. However, the 1930s was also an era in which essential debates about Irish identity and the future of the Irish nation played out, in public discourse and in literature. Memory, in particular, served as an important site for these debates, as the newly independent Irish nation sought to define itself in relation to its turbulent past. O’Faoláin’s stories from this period reflect post-independence disillusionment and draw a desolate picture of a nation at a crossroads. At the same time, however, the stories draw upon revolutionary memories to construct a vision of a new Ireland, one no longer shaped by the legacies of colonialism. Situating O’Faoláin’s work within the context of postcolonial theory, my project argues for the postcolonial short story’s unique ability to represent identities in transition and shape the future of the Irish nation.
Is Faith the Ultimate Divider?: The Intersections Between Religion and Political Behavior in the United States
Date: 2023-01-01
Creator: Ryan Supple
Access: Open access
- This thesis examines the complex relationship between religiosity and voting behavior in the United States. In a country where religion has diminished in importance over time, it seems rather fascinating that it still plays such a large role in the inner-workings of American politics. Chapter One analyzes the varying ways in which scholars have approached emergent political trends between religious groups, particularly with regards to political parties, voting behavior, and government representation. Chapter Two extends this analysis to the American National Election Studies (ANES), a national survey distributed to random samples of Americans during election seasons. The information from the ANES facilitated a more in-depth analysis of how individuals with varying levels of affiliations have interacted with politics, such as ideologies, affiliations, and feelings towards religiously salient political issues. Lastly, Chapter 3 focuses on college-aged students, using both the UCLA's CIRP Freshman Survey and the Bowdoin College Polar Poll, to evaluate how America's educated youth are interacting with politics. These data allowed for a more proper investigation into how a historically unreligious portion of the population interact with religion today, and how this may affect America's religious climate in the future, as students eventually grow into educated professionals and further immerse themselves into politics. Ultimately, this paper suggests that a growing political polarity has coincided with polarization in religion, with two coalitions-- a religious and non religious one moving in opposite directions, thus amounting to further divisions and misunderstandings between the American public.