Showing 71 - 80 of 106 Items

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Miniature of Selective Attention and Memory: Event Related Potentials and the IOR Effect
Selective Attention and Memory: Event Related Potentials and the IOR Effect
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      Date: 2015-05-01

      Creator: Leigh A Andrews

      Access: Access restricted to the Bowdoin Community

        Miniature of Characterisation of the <i>Gryllus bimaculatus</i> nervous system: insights into the role of the Spätzle1 and Spätzle5 proteins in the compensatory plasticity of the CNS
        Characterisation of the Gryllus bimaculatus nervous system: insights into the role of the Spätzle1 and Spätzle5 proteins in the compensatory plasticity of the CNS
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        • Restriction End Date: 2028-06-01

          Date: 2023-01-01

          Creator: Sarah Lührmann

          Access: Access restricted to the Bowdoin Community

            Miniature of Characterizing the Motor Activity Patterns of the Mammalian Thoracic Spinal Cord Neural Network
            Characterizing the Motor Activity Patterns of the Mammalian Thoracic Spinal Cord Neural Network
            This record is embargoed.
              • Embargo End Date: 2027-05-16

              Date: 2024-01-01

              Creator: Sam McClelland

              Access: Embargoed

                Miniature of Brain activity patterns underlying memory confidence
                Brain activity patterns underlying memory confidence

                Date: 2022-04-01

                Creator: Syanah C. Wynn, Erika Nyhus

                Access: Open access

                The primary aim of this review is to examine the brain activity patterns that are related to subjectively perceived memory confidence. We focus on the main brain regions involved in episodic memory: the medial temporal lobe (MTL), prefrontal cortex (PFC), and posterior parietal cortex (PPC), and relate activity in their subregions to memory confidence. How this brain activity in both the encoding and retrieval phase is related to (subsequent) memory confidence ratings will be discussed. Specifically, encoding related activity in MTL regions and ventrolateral PFC mainly shows a positive linear increase with subsequent memory confidence, while dorsolateral and ventromedial PFC activity show mixed patterns. In addition, encoding-related PPC activity seems to only have indirect effects on memory confidence ratings. Activity during retrieval in both the hippocampus and parahippocampal cortex increases with memory confidence, especially during high-confident recognition. Retrieval-related activity in the PFC and PPC show mixed relationships with memory confidence, likely related to post-retrieval monitoring and attentional processes, respectively. In this review, these MTL, PFC, and PPC activity patterns are examined in detail and related to their functional roles in memory processes. This insight into brain activity that underlies memory confidence is important for our understanding of brain–behaviour relations and memory-guided decision making. © 2022 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.
                Miniature of Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP
                Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP

                Date: 2009-11-01

                Creator: Anja Forche, Musetta Steinbach, Judith Berman

                Access: Open access

                Candida albicans is the most prevalent opportunistic fungal pathogen in the clinical setting, causing a wide spectrum of diseases ranging from superficial mucosal lesions to life-threatening deep-tissue infections. Recent studies provide strong evidence that C. albicans possesses an arsenal of genetic mechanisms promoting genome plasticity and that it uses these mechanisms under conditions of nutritional or antifungal drug stress. Two microarray-based methods, single nucleotide polymorphism (SNP) and comparative genome hybridization arrays, have been developed to study genome changes in C. albicans. However, array technologies can be relatively expensive and are not available to every laboratory. In addition, they often generate more data than needed to analyze specific genomic loci or regions. Here, we have developed a set of SNP-restriction fragment length polymorphism (RFLP) (or PCR-RFLP) markers, two per chromosome arm, for C. albicans. These markers can be used to rapidly and accurately detect large-scale changes in the C. albicans genome including loss of heterozygosity (LOH) at single loci, across chromosome arms or across whole chromosomes. Furthermore, skewed SNP-RFLP allelic ratios are indicative of trisomy at heterozygous loci. While less comprehensive than array-based approaches, we propose SNP-RFLP as an inexpensive, rapid, and reliable method to screen strains of interest for possible genome changes. © 2009 Federation of European Microbiological Societies.
                Miniature of Erratum: The 'obligate diploid' Candida albicans forms mating-competent haploids (Nature (2013) 494 (55-59) DOI: 10.1038/nature11865)
                Erratum: The 'obligate diploid' Candida albicans forms mating-competent haploids (Nature (2013) 494 (55-59) DOI: 10.1038/nature11865)

                Date: 2016-02-11

                Creator: Meleah A. Hickman, Guisheng Zeng, Anja Forche, Matthew P. Hirakawa, Darren, Abbey, Benjamin D. Harrison, Yan Ming Wang, Ching Hua Su, Richard J. Bennett, Yue Wang, Judith Berman

                Access: Open access

                Miniature of Ploidy variation in fungi: Polyploidy, aneuploidy, and genome evolution
                Ploidy variation in fungi: Polyploidy, aneuploidy, and genome evolution

                Date: 2017-07-01

                Creator: Robert T. Todd, Anja Forche, Anna Selmecki

                Access: Open access

                The ability of an organism to replicate and segregate its genome with high fidelity is vital to its survival and for the production of future generations. Errors in either of these steps (replication or segregation) can lead to a change in ploidy or chromosome number. While these drastic genome changes can be detrimental to the organism, resulting in decreased fitness, they can also provide increased fitness during periods of stress. A change in ploidy or chromosome number can fundamentally change how a cell senses and responds to its environment. Here, we discuss current ideas in fungal biology that illuminate how eukaryotic genome size variation can impact the organism at a cellular and evolutionary level. One of the most fascinating observations from the past 2 decades of research is that some fungi have evolved the ability to tolerate large genome size changes and generate vast genomic heterogeneity without undergoing canonical meiosis.
                Miniature of The Modulatory Role of the Hyperpolarization-Activated Inward Current and Adenosine A1 - Dopamine D1 Receptor Heteromers on Spinal Locomotor Activity
                The Modulatory Role of the Hyperpolarization-Activated Inward Current and Adenosine A1 - Dopamine D1 Receptor Heteromers on Spinal Locomotor Activity
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                    Date: 2021-01-01

                    Creator: Andrew Moore

                    Access: Access restricted to the Bowdoin Community

                      Miniature of Ultrasonic vocalization playback as an affective assay at both neural and behavioral levels: Implications for understanding adversity-induced emotional dysfunction
                      Ultrasonic vocalization playback as an affective assay at both neural and behavioral levels: Implications for understanding adversity-induced emotional dysfunction
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                          Date: 2023-01-01

                          Creator: Sydney M Bonauto

                          Access: Access restricted to the Bowdoin Community

                            Miniature of Directed Information Flow During Episodic Memory Retrieval at Theta Frequency
                            Directed Information Flow During Episodic Memory Retrieval at Theta Frequency
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                            • Restriction End Date: 2027-06-01

                              Date: 2022-01-01

                              Creator: Patrick F. Bloniasz

                              Access: Access restricted to the Bowdoin Community

                                Neuroscience and Neurobiology Molecular and Cellular Neuroscience Homarus americanus Systems Neuroscience Behavioral Neurobiology cardiac ganglion central pattern generator EEG Cellular and Molecular Physiology Other Neuroscience and Neurobiology neuromodulation Cognitive Neuroscience Developmental Neuroscience Life Sciences Memory early life adversity episodic memory lobster CPG Cognitive control central pattern generators electrophysiology maternal separation modulation parvalbumin temperature Aneuploidy Bioinformatics Candida albicans Computational Neuroscience ERP Gryllus bimaculatus Locomotion anxiety cricket crustacean development myosuppressin neuromuscular junction plasticizer prefrontal cortex sex differences Adolescent Animal Experimentation and Research Attention Brain Cancer borealis Central pattern generators Cognition and Perception Compensatory plasticity EJP Episodic memory Female Humans IOR Information theory Item memory LOH Laboratory and Basic Science Research Loss of heterozygosity Magnetic Resonance Imaging Male Mental Recall Nervous System Diseases Neurosciences Neurotrophins Parvalbumin Source memory Systems and Integrative Physiology Theta Toll receptors Tributyl phosphate (TBP) Young Adult behavior cardiac cardiac muscle cardiac neuromuscular system cold-deactivation crab feedback fictive locomotion ion channels ketamine locomotion motor neuron neuromodulator neuropeptides nitric oxide oscillations plasticity receptors salinity stomatogastric nervous system stretch stretch feedback theta oscillations 5-methylcytosine 5HTTLPR 81-B-5 A-type potassium current AVGSEFLamide Active Adaptation Adult Alpha oscillations American lobster American lobster (Homarus americanus) Amidation Analysis of Variance Anxiety Association Learning Auditory System BDNF Basal ganglia Behavior Beta Rhythm Beta oscillations Biological Clocks Biological Psychology Biology Brain Mapping C-Type Allatostatin C-type allatostatin CNS CPGs Candida Candida krusei Carassius auratus Central Pattern Generator Central Pattern Generators (CPGs) Central pattern generator Chemicals and Drugs Choice Cognitive Psychology Colony phenotype Comparative and Evolutionary Physiology Computational Biology Context specificity Control network Control operations Crustacean Cryptococcus D1R agonist DAT DNA methylation DRG Deafferentation Decision Decision making DeepLabCut Dendritic sprouting Discriminability Distributed networks Dopamine Drift diffusion model Early Life Adversity Electroencephalography Electroencephalography (EEG) Emotions Encoding Environmental Health Environmental Public Health Episodic Memory Episodic retrieval Event-related potentials (ERPs) Evoked Potentials Executive functions Experimental Analysis of Behavior Fitness Fluconazole resistance Font fan Frontal lobes Fungal pathogens GSEFLamide GYS Gamma Genome Report Genome plasticity Genome rearrangement Granger Causality HCN Channel HCN1 channel Heterozygosity Homeostatic plasticity Hyper-variability Hyperpolarization Activated Inward Current Image Processing, Computer-Assisted Imagination Inter-homolog recombination Issue 159 Judgment L-Glutamatic acid Laboratory course Levels of processing Long-Term Memory Lumbar Nerves Majoid Mammalian Spinal Cord Mating type locus Meditation Memory retrieval Memory, Episodic Mice Midazolam Mindfulness Mindfulness meditation Molecular Genetics Motor Control Multimodal Imaging NMJ Navigation Neural Pathways Neural network model Neural plasticity Neuromodulation Neuropeptide Neuropeptides Neuropsychological assessment Neuroscience education Novelty Nyhus Oropharyngeal candidiasis Oscillations Oscillatory signals Other Animal Sciences Oxygen PIR Pattern generator Perceptual match Pharmacology Pharmacy and Pharmaceutical Sciences Photic Stimulation Physical Sciences and Mathematics Physiological Response Physiology Prefrontal cortex Public Health RNA RNA-Seq RT-qPCR Rad51 Rad52 Rad59 Reaction Time Recognition memory Reinforcement learning Response uncertainty Rhythmogenesis Rosmarinic acid (RA) SGRN SLC6A4 SLY neuropeptide family SNP-RFLP STNS Set shifting Sex Differences Sexual dimorphism Single-strand annealing Social approach Spaeztle Spinal Cord Spz Spz Proteins Stomatogastric nervous system Subthalamic nucleus TRPV4 TRPV4 antagonist Task-switching Theta oscillations Thoracic Spinal Network Toll Toll 6-1 Toll Proteins Toll proteins Top-down control Toxicology Transient network Transporters Trunk Motor Behaviors Ultrasonic vocalizations V1a-like receptor Vasotocin Ventrolateral prefrontal cortex Virtual reality Visual Perception Wisconsin Card Sorting Test Working memory ZD7288 active force adenylyl cyclase affective processing afterload pressure alpha power alpha rhythm amine amygdala androgen anxiety-like behavior article ascending neuron attention auditory processing basolateral amygdala behavioral neuroscience bioinformatics bursting stability c-Fos calcium-activated potassium channels cellular neurophysiology central pattern generation central pattern generator (CPG) central pattern generator (CPG) network chill coma circuit compensatory plasticity corticolimbic development corticosterone crash crash temperature cricket embryos curcumin deafferentation decision making dendritic plasticity depression dibutyl phthalate differential gene expression dopamine early-life adversity electrical stimulation electroencephalogram elevated zero maze entrainment estrogen estrogen receptor ethological behaviors evoked response evolution excitatory junction potential executive function flexibility forskolin frontoparietal network functional magnetic resonance imaging gastric mill groupSIFT gryllus bimaculatus heartbeat heartbeat frequency human hyperdopaminergic transmission hyperpolarization-activated inward current in situ hybridization inhibition interneurons intrinsic properties irregularity isolated cardiac ganglion item memory limb bud lobster cardiac ganglion lumbar CPG machine learning majoid mammalian spinal cord medial temporal lobe membrane receptors memory retrieval mindfulness meditation modulatory capacity motor neurons motor output mouse muscle contraction mushroom bodies negative feedback neonatal mouse spinal cord nerve cell nerve cell oscillation neural circuits neuronal excitation neuronal nitric oxide synthase (nNOS) neuropeptide neuroplasticity neuroprotectant neuroprotection neuroscience nitric oxide feedback non-genomic noninvasive neuromodulation normal human octopamine old/new effect oxidative stress patch clamp pattern generator peltier element peptide signaling peripheral nervous system development phasic pheromone plastic pollution post translational modifications post-retrieval monitoring posterior parietal cortex priority journal prothoracic ganglia pyloric filter rPDC reciprocal inhibition recognition renormalized Partial Directed Coherence reproduction restless legs syndrome rhythmic motor output semaphorin sensory feedback sex-specific site(s) of modulation social behavior social preference source retrieval spinal cord stereotaxic stimulation stereotaxic surgery steroid structural plasticity tACS task performance thermal robustness thermosensation theta rhythm transcriptome translational models tyramine ultrasonic vocalization playback unsupervised clustering ventral root ventral roots visual memory visual stimulation y-Aminobutyric acid zebrafish