Showing 711 - 720 of 2039 Items
Components of the Springer fiber and domino tableaux
Date: 2004-02-15
Creator: Thomas Pietraho
Access: Open access
- Consider a complex classical semisimple Lie group along with the set of its nilpotent coadjoint orbits. When the group is of type A, the set of orbital varieties contained in a given nilpotent orbit is described a set of standard Young tableaux. We parameterize both, the orbital varieties and the irreducible components of unipotent varieties in the other classical groups by sets of standard domino tableaux. The main tools are Spaltenstein's results on signed domino tableaux together with Garfinkle's operations on standard domino tableaux. © 2004 Elsevier Inc. All rights reserved.
Event-related potential correlates of interference effects on recognition memory
Date: 2008-02-01
Creator: Kenneth A. Norman
Katharine Tepe
Erika Nyhus
Tim Curran
Access: Open access
- The question of interference (how new learning affects previously acquired knowledge and vice versa) is a central theoretical issue in episodic memory research, but very few human neuroimaging studies have addressed this question. Here, we used event-related potentials (ERPs) to test the predictions of the complementary learning systems (CLS) model regarding how list strength manipulations (strengthening some, but not all, items on a study list) affect recognition memory. Our analysis focused on the FN400 old-new effect, a hypothesized ERP correlate of familiarity-based recognition, and the parietal old-new effect, a hypothesized ERP correlate of recollection-based recognition. As is predicted by the CLS model, increasing list strength selectively reduced the ERP correlate of recollection-based discrimination, leaving the ERP correlate of familiarity-based discrimination intact. In a second experiment, we obtained converging evidence for the CLS model's predictions, using a remember/know test: Increasing list strength reduced recollection-based discrimination but did not reduce familiarity-based discrimination. Copyright 2008 Psychonomic Society, Inc.
Level-rank duality of the U(N) WZW model, Chern-Simons theory, and 2d qYM theory
Date: 2007-06-01
Creator: Stephen G. Naculich
Howard J. Schnitzer
Access: Open access
- We study the WZW, Chern-Simons, and 2d qYM theories with gauge group U(N). The U(N) WZW model is only well-defined for odd level K, and this model is shown to exhibit level-rank duality in a much simpler form than that for SU(N). The U(N) Chern-Simons theory on Seifert manifolds exhibits a similar duality, distinct from the level-rank duality of SU(N) Chern-Simons theory on S 3. When q ≤ e2πi/(N+K), the observables of the 2d U(N) qYM theory can be expressed as a sum over a finite subset of U(N) representations. When N and K are odd, the qYM theory exhibits N K duality, provided q ≤ e2πi/(N+K) and θ ≤ 0 mod 2π/(N + K). © SISSA 2007.
Level-rank duality of untwisted and twisted D-branes
Date: 2006-05-15
Creator: Stephen G. Naculich
Howard J. Schnitzer
Access: Open access
- Level-rank duality of untwisted and twisted D-branes of WZW models is explored. We derive the relation between D0-brane charges of level-rank dual untwisted D-branes of over(su, ̂) ( N )K and over(sp, ̂) ( n )k, and of level-rank dual twisted D-branes of over(su, ̂) ( 2 n + 1 )2 k + 1. The analysis of level-rank duality of twisted D-branes of over(su, ̂) ( 2 n + 1 )2 k + 1 is facilitated by their close relation to untwisted D-branes of over(sp, ̂) ( n )k. We also demonstrate level-rank duality of the spectrum of an open string stretched between untwisted or twisted D-branes in each of these cases. © 2006 Elsevier B.V. All rights reserved.
Evolution of pathogenicity and sexual reproduction in eight Candida genomes
Date: 2009-06-04
Creator: Geraldine Butler
Matthew D. Rasmussen
Michael F. Lin
Manuel A.S. Santos
Sharadha, Sakthikumar
Carol A. Munro
Esther Rheinbay
Manfred Grabherr
Anja Forche
Jennifer L. Reedy
Ino Agrafioti
Martha B. Arnaud
Steven Bates
Alistair J.P. Brown
Sascha Brunke
Maria C. Costanzo
David A. Fitzpatrick
Piet W.J. De Groot
David Harris
Lois L. Hoyer
Bernhard Hube
Frans M. Klis
Chinnappa Kodira
Nicola Lennard
Mary E. Logue
Ronny Martin
Aaron M. Neiman
Elissavet Nikolaou
Michael A. Quail
Janet Quinn
Maria C. Santos
Access: Open access
- Candida species are the most common cause of opportunistic fungal infection worldwide. Here we report the genome sequences of six Candida species and compare these and related pathogens and non-pathogens. There are significant expansions of cell wall, secreted and transporter gene families in pathogenic species, suggesting adaptations associated with virulence. Large genomic tracts are homozygous in three diploid species, possibly resulting from recent recombination events. Surprisingly, key components of the mating and meiosis pathways are missing from several species. These include major differences at the mating-type loci (MTL); Lodderomyces elongisporus lacks MTL, and components of the a1/α2 cell identity determinant were lost in other species, raising questions about how mating and cell types are controlled. Analysis of the CUG leucine-to-serine genetic-code change reveals that 99% of ancestral CUG codons were erased and new ones arose elsewhere. Lastly, we revise the Candida albicans gene catalogue, identifying many new genes. © 2009 Macmillan Publishers Limited. All rights reserved.
Evolution of the interaction between Hox genes and a downstream target
Date: 1998-05-07
Creator: Michael F. Palopoli
Nipam H. Patel
Access: Open access
- Segmental identifies along the insect body depend on the activities of Hox genes [1,2]. In Drosophila melanogaster, one well-studied Hox regulatory target is Distal-less (DII), which Is required for the development of distel limb structures [3]. In abdominal segments, DII transcription is prevented when Hox proteins of the Bithorax Complex (BX-C) bind to cis-regulatory elements upstream of the DII transcription start site [4,5]. Previous evolutionary comparisons of gene expression patterns suggest that this direct repression is conserved between Diptera and Lepidoptera, but is absent in the Crustacea [6,7]. We examined gene expression patterns in three orders of hexapods, all of which develop abdominal appendages, in order to determine when the strong repressive interaction between BX-C proteins and DII appeared during evolution. In each of the species examined, DII expression was initiated in abdominal cells despite the presence of high levels of BX-C proteins. It appears that the strong repressive effects of BX-C proteins on DII expression arose relatively late in insect evolution. We suggest that the regulatory interaction between the BX-C genes and DII has evolved within the hexapods in a complex, segment-specific manner.
CHY representations for gauge theory and gravity amplitudes with up to three massive particles
Date: 2015-05-28
Creator: Stephen G. Naculich
Access: Open access
- We show that a wide class of tree-level scattering amplitudes involving scalars, gauge bosons, and gravitons, up to three of which may be massive, can be expressed in terms of a Cachazo-He-Yuan representation as a sum over solutions of the scattering equations. These amplitudes, when expressed in terms of the appropriate kinematic invariants, are independent of the masses and therefore identical to the corresponding massless amplitudes.
An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1
Date: 2008-05-01
Creator: Anna Selmecki
Maryam Gerami-Nejad
Carsten Paulson
Anja Forche
Judith, Berman
Access: Open access
- Acquired azole resistance is a serious clinical problem that is often associated with the appearance of aneuploidy and, in particular, with the formation of an isochromosome [i(5L)] in the fungal opportunist Candida albicans. Here we exploited a series of isolates from an individual patient during the rapid acquisition of fluconazole resistance (FluR). Comparative genome hybridization arrays revealed that the presence of two extra copies of Chr5L, on the isochromosome, conferred increased FluR and that partial truncation of Chr5L reduced FluR. In vitro analysis of the strains by telomere-mediated truncations and by gene deletion assessed the contribution of all Chr5L genes and of four specific genes. Importantly, ERG11 (encoding the drug target) and a hyperactive allele of TAC1 (encoding a transcriptional regulator of drug efflux pumps) made independent, additive contributions to FluR in a gene copy number-dependent manner that was not different from the contributions of the entire Chr5L arm. Thus, the major mechanism by which i(5L) formation causes increased azole resistance is by amplifying two genes: ERG11 and TAC1. © 2008 The Authors.
Clarifying (Opportunity) Costs
Date: 2015-05-01
Creator: Daniel F. Stone
Access: Open access
- Opportunity cost is widely considered to be a fundamental concept in economics. But the definition of the term continues to be both unclear and controversial. I describe how the term is widely used in two distinct ways, both in academic and non-academic contexts. I propose a practical way for educators to clarify the concept and related terminology.