Showing 51 - 60 of 722 Items
Sign changes of Fourier coefficients of Hilbert modular forms
Date: 2014-01-01
Creator: Jaban Meher
Naomi Tanabe
Access: Open access
- Sign changes of Fourier coefficients of various modular forms have been studied. In this paper, we analyze some sign change properties of Fourier coefficients of Hilbert modular forms, under the assumption that all the coefficients are real. The quantitative results on the number of sign changes in short intervals are also discussed. © 2014 Elsevier Inc.
Simple-current symmetries, rank-level duality, and linear skein relations for Chern-Simons graphs
Date: 1993-04-12
Creator: Stephen G. Naculich
Harold A. Riggs
Howard J. Schnitzer
Access: Open access
- A previously proposed two-step algorithm for calculating the expectation values of arbitrary Chern-Simons graphs fails to determine certain crucial signs. The step which involves calculating tetrahedra by solving certain non-linear equations is repaired by introducing additional linear equations. The step which involves reducing arbitrary graphs to sums of products of tetrahedra remains seriously disabled, apart from a few exceptional cases. As a first step towards a new algorithm for general graphs we find useful linear equations for those special graphs which support knots and links. Using the improved set of equations for tetrahedra we examine the symmetries between tetrahedra generated by arbitrary simple currents. Along the way we describe the simple, classical origin of simple-current charges. The improved skein relations also lead to exact identities between planar tetrahedra in level K G(N) and level N G(K) Chern-Simons theories, where G(N) denotes a classical group. These results are recast as WZW braid-matrix identities and as identities between quantum 6-jsymbols at appropriate roots of unity. We also obtain the transformation properties of arbitrary graphs, knots, and links under simple-current symmetries and rank-level duality. For links with knotted components this requires precise control of the braid eigenvalue permutation signs, which we obtain from plethysm and an explicit expression for the (multiplicity-free) signs, valid for all compact gauge groups and all fusion products. © 1993.
A genome-wide screen identifies genes that affect somatic homolog pairing in drosophila
Date: 2012-07-01
Creator: Jack R. Bateman
Erica Larschan
Ryan D'Souza
Lauren S. Marshall
Kyle E., Dempsey
Justine E. Johnson
Barbara G. Mellone
Mitzi I. Kuroda
Access: Open access
- In Drosophila and other Dipterans, homologous chromosomes are in close contact in virtually all nuclei, a phenomenon known as somatic homolog pairing. Although homolog pairing has been recognized for over a century, relatively little is known about its regulation. We performed a genome-wide RNAibased screen that monitored the X-specific localization of the male-specific lethal (MSL) complex, and we identified 59 candidate genes whose knockdown via RNAi causes a change in the pattern of MSL staining that is consistent with a disruption of X-chromosomal homolog pairing. Using DNA fluorescent in situ hybridization (FISH), we confirmed that knockdown of 17 of these genes has a dramatic effect on pairing of the 359 bp repeat at the base of the X. Furthermore, dsRNAs targeting Pr-set7, which encodes an H4K20 methyltransferase, cause a modest disruption in somatic homolog pairing. Consistent with our results in cultured cells, a classical mutation in one of the strongest candidate genes, pebble (pbl), causes a decrease in somatic homolog pairing in developing embryos. Interestingly, many of the genes identified by our screen have known roles in diverse cell-cycle events, suggesting an important link between somatic homolog pairing and the choreography of chromosomes during the cell cycle. © 2012 Bowers et al.
Inelastic channels in WW scattering
Date: 1993-01-01
Creator: S. G. Naculich
C. P. Yuan
Access: Open access
- If the electroweak symmetry-breaking sector becomes strongly interacting at high energies, it can be probed through longitudinal W scattering. We present a model with many inelastic channels in the WLWL scattering process, corresponding to the production of heavy fermion pairs. These heavy fermions affect the elastic scattering of WL's by propagating in loops, greatly reducing the amplitudes in some charge channels. We conclude that the symmetry-breaking sector cannot be fully explored by using, for example, the WL±WL± mode alone, even when no resonance is present; all WLWL→WLWL scattering modes must be measured. © 1993 The American Physical Society.
With age comes immaturity: Do countries with older populations issue shorter maturity debt?
Date: 2021-12-01
Creator: Gonca Senel
Mark L.J. Wright
Access: Open access
- Recent work has found that countries with older populations face steeper yield curves and issue shorter maturity debt than do younger countries. We reexamine these findings using a new database of public debt maturity and yields for OECD countries. We first show that the behavior of eurozone countries in the pre-euro period drives these results. Next, including more recent data from the post-euro period, we show that the relationship between population age, maturity, and yield curve slopes disappears. This finding is robust to excluding high-credit-risk countries. Last, we show that these patterns reemerge after the European debt crisis, suggesting that eurozone capital markets have resegmented.
Molecular basis of the copulatory plug polymorphism in Caenorhabditis elegans
Date: 2008-08-21
Creator: Michael F. Palopoli
Matthew V. Rockman
Aye TinMaung
Camden Ramsay
Stephen, Curwen
Andrea Aduna
Jason Laurita
Leonid Kruglyak
Access: Open access
- Heritable variation is the raw material for evolutionary change, and understanding its genetic basis is one of the central problems in modern biology. We investigated the genetic basis of a classic phenotypic dimorphism in the nematode Caenorhabditis elegans. Males from many natural isolates deposit a copulatory plug after mating, whereas males from other natural isolates-including the standard wild-type strain (N2 Bristol) that is used in most research laboratories-do not deposit plugs. The copulatory plug is a gelatinous mass that covers the hermaphrodite vulva, and its deposition decreases the mating success of subsequent males. We show that the plugging polymorphism results from the insertion of a retrotransposon into an exon of a novel mucin-like gene, plg-1, whose product is a major structural component of the copulatory plug. The gene is expressed in a subset of secretory cells of the male somatic gonad, and its loss has no evident effects beyond the loss of male mate-guarding. Although C. elegans descends from an obligate-outcrossing, male?female ancestor, it occurs primarily as self-fertilizing hermaphrodites. The reduced selection on male-male competition associated with the origin of hermaphroditism may have permitted the global spread of a loss-of-function mutation with restricted pleiotropy. ©2008 Macmillan Publishers Limited. All rights reserved.
Partisan selective engagement: Evidence from Facebook
Date: 2020-09-01
Creator: Marcel Garz
Jil Sörensen
Daniel F. Stone
Access: Open access
- This study investigates the effects of variation in “congeniality” of news on Facebook user engagement (likes, shares, and comments). We compile an original data set of Facebook posts by 84 German news outlets on politicians that were investigated for criminal offenses from January 2012 to June 2017. We also construct an index of each outlet's media slant by comparing the language of the outlet with that of the main political parties, which allows us to measure the congeniality of the posts. We find that user engagement with congenial posts is higher than with uncongenial ones, especially in terms of likes. The within-outlet, within-topic design allows us to infer that the greater engagement with congenial news is likely driven by psychological and social factors, rather than a desire for accurate or otherwise instrumental information.
Aneuploid chromosomes are highly unstable during DNA transformation of candida albicans∇
Date: 2009-10-01
Creator: Kelly Bouchonville
Anja Forche
Karen E.S. Tang
Anna Selmecki
Judith, Berman
Access: Open access
- Candida albicans strains tolerate aneuploidy, historically detected as karyotype alterations by pulsed-fleld gel electrophoresis and more recently revealed by array comparative genome hybridization, which provides a comprehensive and detailed description of gene copy number. Here, we first retrospectively analyzed 411 expression array experiments to predict the frequency of aneuploidy in different strains. As expected, significant levels of aneuploidy were seen in strains exposed to stress conditions, including UV light and/or sorbose treatment, as well as in strains that are resistant to antifungal drugs. More surprisingly, strains that underwent transformation with DNA displayed the highest frequency of chromosome copy number changes, with strains that were initially aneuploid exhibiting ∼3-fold more copy number changes than strains that were initially diploid. We then prospectively analyzed the effect of lithium acetate (LiOAc) transformation protocols on the stability of trisomie chromosomes. Consistent with the retrospective analysis, the proportion of karyotype changes was highly elevated in strains carrying aneuploid chromosomes. We then tested the hypothesis that stresses conferred by heat and/or LiOAc exposure promote chromosome number changes during DNA transformation procedures. Indeed, a short pulse of very high temperature caused frequent gains and losses of multiple chromosomes or chromosome segments. Furthermore, milder heat exposure over longer periods caused increased levels of loss of heterozygosity. Nonetheless, aneuploid chromosomes were also unstable when strains were transformed by electroporation, which does not include a heat shock step. Thus, aneuploid strains are particularly prone to undergo changes in chromosome number during the stresses of DNA transformation protocols. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
Intron Size Correlates Positively with Recombination Rate in Caenorhabditis elegans
Date: 2004-03-01
Creator: Anuphap Prachumwat
Laura DeVincentis
Michael F. Palopoli
Access: Open access
- A negative correlation between intron size and recombination rate has been reported for the Drosophila melanogaster and human genomes. Population-genetic models suggest that this pattern could be caused by an interaction between recombination rate and the efficacy of natural selection. To test this idea, we examined variation in intron size and recombination rate across the genome of the nematode Caenorhabditis elegans. Interestingly, we found that intron size correlated positively with recombination rate in this species.
Next-to-soft corrections to high energy scattering in QCD and gravity
Date: 2017-01-01
Creator: A. Luna
S. Melville
S. G. Naculich
C. D. White
Access: Open access
- We examine the Regge (high energy) limit of 4-point scattering in both QCD and gravity, using recently developed techniques to systematically compute all corrections up to next-to-leading power in the exchanged momentum i.e. beyond the eikonal approximation. We consider the situation of two scalar particles of arbitrary mass, thus generalising previous calculations in the literature. In QCD, our calculation describes power-suppressed corrections to the Reggeisation of the gluon. In gravity, we confirm a previous conjecture that next-to-soft corrections correspond to two independent deflection angles for the incoming particles. Our calculations in QCD and gravity are consistent with the well-known double copy relating amplitudes in the two theories.