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Miniature of History lessons: The early development of intellectual property institutions in the United States
History lessons: The early development of intellectual property institutions in the United States

Date: 2001-01-01

Creator: B. Zorina Khan

Kenneth L. Sokoloff

Access: Open access

Miniature of Measurement of the tau lepton electronic branching fraction
Measurement of the tau lepton electronic branching fraction

Date: 1992-01-01

Creator: D. S. Akerib

B. Barish

M. Chadha

D. F. Cowen

G., Eigen

J. S. Miller

J. Urheim

A. J. Weinstein

D. Acosta

G. Masek

B. Ong

H. Paar

M. Sivertz

A. Bean

J. Gronberg

R. Kutschke

S. Menary

R. J. Morrison

H. N. Nelson

J. D. Richman

H. Tajima

D. Schmidt

D. Sperka

M. S. Witherell

M. Procario

S. Yang

M. Daoudi

W. T. Ford

D. R. Johnson

K. Lingel

M. Lohner

Access: Open access

The tau lepton electron branching fraction has been measured with the CLEO II detector at the Cornell Electron Storage Ring as Be=0.17490.00140.0022, with the first error statistical and the second systematic. The measurement involves counting electron-positron annihilation events in which both taus decay to electrons, and normalizing to the number of tau-pair decays expected from the measured luminosity. Detected photons in these events constitute a definitive observation of tau decay radiation. © 1992 The American Physical Society.
Miniature of Neuropeptidergic signaling in the American Lobster Homarus Americanus: New insights from high-throughput nucleotide sequencing
Neuropeptidergic signaling in the American Lobster Homarus Americanus: New insights from high-throughput nucleotide sequencing

Date: 2015-12-01

Creator: Andrew E. Christie

Megan Chi

Tess J. Lameyer

Micah G. Pascual

Devlin N., Shea

Meredith E. Stanhope

David J. Schulz

Patsy S. Dickinson

Access: Open access

Peptides are the largest and most diverse class of molecules used for neurochemical communication, playing key roles in the control of essentially all aspects of physiology and behavior. The American lobster, Homarus americanus, is a crustacean of commercial and biomedical importance; lobster growth and reproduction are under neuropeptidergic control, and portions of the lobster nervous system serve as models for understanding the general principles underlying rhythmic motor behavior (including peptidergic neuromodulation). While a number of neuropeptides have been identified from H. americanus, and the effects of some have been investigated at the cellular/systems levels, little is currently known about the molecular components of neuropeptidergic signaling in the lobster. Here, a H. americanus neural transcriptome was generated and mined for sequences encoding putative peptide precursors and receptors; 35 precursor- and 41 receptor-encoding transcripts were identified. We predicted 194 distinct neuropeptides from the deduced precursor proteins, including members of the adipokinetic hormone-corazonin-like peptide, allatostatin A, allatostatin C, bursicon, CCHamide, corazonin, crustacean cardioactive peptide, crustacean hyperglycemic hormone (CHH), CHH precursor-related peptide, diuretic hormone 31, diuretic hormone 44, eclosion hormone, FLRFamide, GSEFLamide, insulin-like peptide, intocin, leucokinin, myosuppressin, neuroparsin, neuropeptide F, orcokinin, pigment dispersing hormone, proctolin, pyrokinin, SIFamide, sulfakinin and tachykinin-related peptide families. While some of the predicted peptides are known H. americanus isoforms, most are novel identifications, more than doubling the extant lobster neuropeptidome. The deduced receptor proteins are the first descriptions of H. americanus neuropeptide receptors, and include ones for most of the peptide groups mentioned earlier, as well as those for ecdysistriggering hormone, red pigment concentrating hormone and short neuropeptide F. Multiple receptors were identified for most peptide families. These data represent the most complete description of the molecular underpinnings of peptidergic signaling in H. americanus, and will serve as a foundation for future gene-based studies of neuropeptidergic control in the lobster.
Miniature of Distinct or shared actions of peptide family isoforms: I. Peptidespecific actions of pyrokinins in the lobster cardiac neuromuscular system
Distinct or shared actions of peptide family isoforms: I. Peptidespecific actions of pyrokinins in the lobster cardiac neuromuscular system

Date: 2015-09-01

Creator: Patsy S. Dickinson

Anirudh Sreekrishnan

Molly A. Kwiatkowski

Andrew E. Christie

Access: Open access

Although the crustacean heart is modulated by a large number of peptides and amines, few of these molecules have been localized to the cardiac ganglion itself; most appear to reach the cardiac ganglion only by hormonal routes. Immunohistochemistry in the American lobster Homarus americanus indicates that pyrokinins are present not only in neuroendocrine organs ( pericardial organ and sinus gland), but also in the cardiac ganglion itself, where pyrokinin-positive terminals were found in the pacemaker cell region, as well as surrounding the motor neurons. Surprisingly, the single pyrokinin peptide identified from H. americanus, FSPRLamide, which consists solely of the conserved FXPRLamide residues that characterize pyrokinins, did not alter the activity of the cardiac neuromuscular system. However, a pyrokinin from the shrimp Litopenaeus vannamei [ADFAFNPRLamide, also known as Penaeus vannamei pyrokinin 2 (PevPK2)] increased both the frequency and amplitude of heart contractions when perfused through the isolated whole heart. None of the other crustacean pyrokinins tested (another from L. vannamei and two from the crab Cancer borealis) had any effect on the lobster heart. Similarly, altering the PevPK2 sequence either by truncation or by the substitution of single amino acids resulted in much lower or no activity in all cases; only the conservative substitution of serine for alanine at position 1 resulted in any activity on the heart. Thus, in contrast to other systems (cockroach and crab) in which all tested pyrokinins elicit similar bioactivities, activation of the pyrokinin receptor in the lobster heart appears to be highly isoform specific.
Miniature of Study of continuum D*+ spin alignment
Study of continuum D*+ spin alignment

Date: 1991-01-01

Creator: Y. Kubota

J. K. Nelson

D. Perticone

R. Poling

S., Schrenk

G. Crawford

R. Fulton

T. Jensen

D. R. Johnson

H. Kagan

R. Kass

R. Malchow

F. Morrow

J. Whitmore

P. Wilson

D. Bortoletto

D. Brown

J. Dominick

R. L. McIlwain

D. H. Miller

M. Modesitt

C. R. Ng

S. F. Schaffner

E. I. Shibata

I. P.J. Shipsey

M. Battle

H. Kroha

K. Sparks

E. H. Thorndike

C. H. Wang

M. S. Alam

Access: Open access

The spin alignment of D*+ mesons produced in e+e- annihilation at s=10.5 GeV is obtained from a study of the angular distribution of the decay D*+D0+. The alignment is studied as a function of momentum and compared to theoretical predictions. We find an average value of the spin alignment parameter of =0.040.020.01. We obtain a model-dependent measurement of the probability of producing a vector particle PV=0.770.020.01 for D mesons. © 1991 The American Physical Society.
Miniature of Measurement of the c+ decay-asymmetry parameter
Measurement of the c+ decay-asymmetry parameter

Date: 1990-01-01

Creator: P. Avery

D. Besson

L. Garren

J. Yelton

K., Kinoshita

F. M. Pipkin

M. Procario

Richard Wilson

J. Wolinski

D. Xiao

Y. Zhu

R. Ammar

P. Baringer

D. Coppage

R. Davis

P. Haas

M. Kelly

N. Kwak

Ha Lam

S. Ro

Y. Kubota

J. K. Nelson

D. Perticone

R. Poling

R. Fulton

T. Jensen

D. R. Johnson

H. Kagan

R. Kass

F. Morrow

J. Whitmore

Access: Open access

We report a measurement of polarization in the two-body decay c+, in nonresonant e+e- interactions from data taken with the CLEO detector. Using these data we have determined the parity-violating asymmetry decay parameter c to be -1.0-0.0+0.4. We see no evidence for significant c+ polarization. © 1990 The American Physical Society.
Miniature of Identification of SYWKQCAFNAVSCFamide: A broadly conserved crustacean C-type allatostatin-like peptide with both neuromodulatory and cardioactive properties
Identification of SYWKQCAFNAVSCFamide: A broadly conserved crustacean C-type allatostatin-like peptide with both neuromodulatory and cardioactive properties

Date: 2009-04-15

Creator: Patsy S. Dickinson

Teerawat Wiwatpanit

Emily R. Gabranski

Rachel J. Ackerman

Jake S., Stevens

Christopher R. Cashman

Elizabeth A. Stemmler

Andrew E. Christie

Access: Open access

The allatostatins comprise three structurally distinct peptide families that regulate juvenile hormone production by the insect corpora allata. A-type family members contain the C-terminal motif -YXFGLamide and have been found in species from numerous arthropod taxa. Members of the B-type family exhibit a -WX6Wamide C-terminus and, like the A-type peptides, appear to be broadly conserved within the Arthropoda. By contrast, members of the C-type family, typified by the unblocked C-terminus -PISCF, a pyroglutamine blocked N-terminus, and a disulfide bridge between two internal Cys residues, have only been found in holometabolous insects, i.e. lepidopterans and dipterans. Here, using transcriptomics, we have identified SYWKQCAFNAVSCFamide (disulfide bridging predicted between the two Cys residues), a known honeybee and water flea C-typelike peptide, from the American lobster Homarus americanus (infraorder Astacidea). Using matrix assisted laser desorption/ionization Fourier transform mass spectrometry (MALDI-FTMS), a mass corresponding to that of SYWKQCAFNAVSCFamide was detected in the H. americanus brain, supporting the existence of this peptide and its theorized structure. Furthermore, SYWKQCAFNAVSCFamide was detected by MALDI-FTMS in neural tissues from five additional astacideans as well as 19 members of four other decapod infraorders (i.e. Achelata, Anomura, Brachyura and Thalassinidea), suggesting that it is a broadly conserved decapod peptide. In H. americanus, SYWKQCAFNAVSCFamide is capable of modulating the output of both the pyloric circuit of the stomatogastric nervous system and the heart. This is the first demonstration of bioactivity for this peptide in any species.
Miniature of Maximally rotating supermassive stars at the onset of collapse: Effects of gas pressure
Maximally rotating supermassive stars at the onset of collapse: Effects of gas pressure

Date: 2019-09-21

Creator: Kenneth A. Dennison

Thomas W. Baumgarte

Stuart L. Shapiro

Access: Open access

The ‘direct collapse’ scenario has emerged as a promising evolutionary track for the formation of supermassive black holes early in the Universe. In an idealized version of such a scenario, a uniformly rotating supermassive star spinning at the mass-shedding (Keplerian) limit collapses gravitationally after it reaches a critical configuration. Under the assumption that the gas is dominated by radiation pressure, this critical configuration is characterized by unique values of the dimensionless parameters J/M2 and Rp/M, where J is the angular momentum, Rp the polar radius, and M the mass. Motivated by a previous perturbative treatment, we adopt a fully non-linear approach to evaluate the effects of gas pressure on these dimensionless parameters for a large range of masses. We find that gas pressure has a significant effect on the critical configuration even for stellar masses as large as M ~ 106 MO. We also calibrate two approximate treatments of the gas pressure perturbation in a comparison with the exact treatment, and find that one commonly used approximation in particular results in increasing deviations from the exact treatment as the mass decreases, and the effects of gas pressure increase. The other approximation, however, proves to be quite robust for all masses M >~ 104 MO.
Miniature of RPCH modulation of a multi-oscillator network: Effects on the pyloric network of the spiny lobster
RPCH modulation of a multi-oscillator network: Effects on the pyloric network of the spiny lobster

Date: 2001-01-01

Creator: Patsy S. Dickinson

Jane Hauptman

John Hetling

Anand Mahadevan

Access: Open access

The neuropeptide red pigment concentrating hormone (RPCH), which we have previously shown to activate the cardiac sac motor pattern and lead to a conjoint gastric mill-cardiac sac pattern in the spiny lobster Panulirus, also activates and modulates the pyloric pattern. Like the activity of gastric mill neurons in RPCH, the pattern of activity in the pyloric neurons is considerably more complex than that seen in control saline. This reflects the influence of the cardiac sac motor pattern, and particularly the upstream inferior ventricular (IV) neurons, on many of the pyloric neurons. RPCH intensifies this interaction by increasing the strength of the synaptic connections between the IV neurons and their targets in the stomatogastric ganglion. At the same time, RPCH enhances postinhibitory rebound in the lateral pyloric (LP) neuron. Taken together, these factors largely explain the complex pyloric pattern recorded in RPCH in Panulirus.
Miniature of Analytical tendex and vortex fields for perturbative black hole initial data
Analytical tendex and vortex fields for perturbative black hole initial data

Date: 2012-10-26

Creator: Kenneth A. Dennison

Thomas W. Baumgarte

Access: Open access

Tendex and vortex fields, defined by the eigenvectors and eigenvalues of the electric and magnetic parts of the Weyl curvature tensor, form the basis of a recently developed approach to visualizing spacetime curvature. In particular, this method has been proposed as a tool for interpreting results from numerical binary black hole simulations, providing a deeper insight into the physical processes governing the merger of black holes and the emission of gravitational radiation. Here we apply this approach to approximate but analytical initial data for both single boosted and binary black holes. These perturbative data become exact in the limit of small boost or large binary separation. We hope that these calculations will provide additional insight into the properties of tendex and vortex fields and will form a useful test for future numerical calculations. © 2012 American Physical Society.

united states history political history oral history law and politics exhibition catalog majority leader fine arts administrative staff american art and architecture maine gubernatorial campaign (1974) american maine politics u.s. senate culture bowdoin college u.s. senate campaign (1982) u.s. senate retirement painting health care maine 20th century legal career mitchell family muskie, edmund s. u.s. senators waterville (me.) history of art, architecture, and archaeology iran-contra modern art and architecture mitchell institute prints dole, robert j. humor social and behavioral sciences tennis contemporary art democratic senatorial campaign committee driving clinton, william j. drawing middle east u.s. senate appointment (1980) cardiac ganglion friends travel clean air act cohen, william s. collection catalog education homarus americanus neuropeptide american politics comparative politics cory, gayle finance committee fundraising history international relations maine democratic party 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plant biology plant sciences polarization politics politics and social change pollution presidential campaign (1992) private collection public economics race rt-pcr social policy sociology of culture sri lanka stomatogastric ganglion terrestrial and aquatic ecology u.s. representatives urban, community, and regional planning veterans' affairs committee watercolor women's studies zebrafish absorption adults african american studies american studies ancient ancient history, greek and roman through late antiquity aneuploidy architecture argentina art asian history assessment astyanax attentional bias authoritarianism baker, howard h., jr. bath iron works (biw) behavioral economics benefit sharing bioinformatics biology bipartisan policy center black holes brazil breather british isles bush, george h.w. c-type allatostatin candida albicans caribbean literature caribbean region caribbean women writers catalog cell biology chafee, john h. christian denominations and sects civic and community engagement clonal plant cognitive bias modification cognitive psychology colonization comparative and evolutionary physiology corporate social responsibility costa rica counterinsurgency cpg defense and security studies democracy diaspora dramatic literature, criticism and theory drawings eeg eelgrass el salvador emery, david f. environmental studies episodic memory ethics evolution f10 - trade: general feedback femininities feminism field theories in higher dimensions film and media studies forests french and francophone language and literature indigenous studies international internet governance invasive jewish studies journalism l-functions labor economics land use change landscape painting latin american languages and societies latin american women writers law literature in english, north america macroeconomics masculinities mass spectrometry matrix models medals media bias medicine and health memoir memory military history minimization mitochondria modulation nature and society 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transvection trauma unequal parameter iwahori-hecke algebra urban studies women and society women writers 17th century 21st century 5‐bisphosphate carboxylase/oxygenase adaptation address adolescencia femenina ads-cft correspondence afghanistan african national congress africana studies aging almost convexity alumni american art amine analysis analytical chemistry anatomical plasticity animals anxiety applied mathematics apsgflgmramide apsgflgmrg aquaculture archaeological anthropology armed services committee arms control art practice asian studies astrophysics and astronomy attention training auditory system backbone carbonyl oxygens background history bacteria basins of attraction behavior berlin biblical studies bifurcations bio-optics bioacoustics biochemistry biomass bioorthogonal chemistry bodies buildings buried arginine c-graph automatic group calcification campaign finance campaigns canada cancer borealis tachykinin-related peptide cancer irroratus cancer productus carbon carbon cycling carbonic anhydrase carbonyl sulfide cardiac muscle cardiotropic peptide caribbean languages and societies caribe catalysis cdna cell expansion central america change charcoal chemistry child psychology children chile chlorophyll christianity chronic tic disorder clean water act clonal growth cloud forest coevolution coffin, frank cold war computational chemistry computer sciences conflict conservation planning constitutional tools constraint continental philosophy cooperation coronavirus corporate governance cosmology crab cricket criminal law criminal procedure criminology and criminal justice critical and cultural studies critical habitat cuba cuerpos curriculum and social inquiry dance decision-making democratic steering committee demodex development studies developmental psychology dft dickey-lincoln project digital authoritarianism dissolved organic carbon dlx dynamical systems eavesdropping ecology economic policy ecotourism education policy educational methods ejp election law elmo empowerment enolase entomology environmental indicators and impact assessment environmental law environmental monitoring epistemology equality erp escritoras escritoras caribeñas escritoras latinoamericanas ethics and political philosophy european languages and societies exchange rate exhibition catalogues expenditures family family, life course, and society feminidades filibuster firn air fisheries fitness folklore forest biology free trade french fresh water studies furniture game theory genet genetics and genomics geographic information sciences geometry and topology german literature girlhood girls glyceraldehyde‐3‐phosphate dehydrogenase glycosylation government governmental affairs committee graph automatic group grief growth growth and development gryllus bimaculatus género harmonic analysis and representation harpswell sound health economics helicobacter pylori hepatopancreas heterozygosity higher education administration hilbert modular forms histamine 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heterozygosity lyft lyndon johnson lysozyme maine republican party majoid manduca sexta-type allatostatin manganese superoxide dismutase mannose marginalization mascilinidades mathematical model mathematics matrix assisted laser desorption/ionization-fourier transform mass spectrometry (maldi-ftms) matrix assisted laser desorption/ionizaton fourier transform mass spectrometry matrix assisted laser desorption/ionizaton fourier transform mass spectrometry (maldi-ftms) media medieval medieval studies memorialization memory retrieval midgut epithelial endocrine signaling midline guidance military mindfulness mindfulness meditation mitchell, sally models and methods modern literature modernism molecular biology molecular genetics molecular marker monteverde morphogenesis morris-lecar model mujer y sociedad multicultural psychology multiple hydrogen bonds muskie senate reelection campaign (1976) nash equilibrium nation native native foster and adoptive parents natural language processing 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afrocaribbean philosohy afrocaribbean religions afrocaribbean women afterload agn agricultural inputs ai alexander alexandrian judaism alfond, harold algebra algebraic number theory algeria algerian literature ali smith allatostatin allatostatin c allatostatin c receptors alleghanian orogeny alliances almost convex alt-right alternative stable states aluminum-containing adjuvant amalgamated cooperative amazon amd american art and architecture|art education|contemporary art|photography|exhibition catalog|photography|john mckee|abe morell|american|20th century american art and architecture|fine arts|modern art and architecture|photography|exhibition catalog|john mckee|photography|landscape photography|american|20th century american art and architecture|modern art and architecture|photography|exhibition catalog|david batchelder|photography|american|20th century american art and architecture|modern art and architecture|photography|exhibition catalog|todd webb|photography|new 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