Showing 191 - 200 of 2040 Items
Date: 1991-01-01
Creator: R. Morrison
D. Schmidt
M. Procario
D. R. Johnson
K., Lingel
P. Rankin
J. G. Smith
J. Alexander
M. Artuso
C. Bebek
K. Berkelman
D. Besson
T. E. Browder
D. G. Cassel
E. Cheu
D. M. Coffman
P. S. Drell
R. Ehrlich
R. S. Galik
M. Garcia-Sciveres
B. Geiser
B. Gittelman
S. W. Gray
D. L. Hartill
B. K. Heltsley
K. Honscheid
J. Kandaswamy
N. Katayama
D. L. Kreinick
J. D. Lewis
G. S. Ludwig
Access: Open access
- Using the CsI calorimeter of the CLEO II detector, the spin triplet b(2P) states are observed in (3S) radiative decays with much higher statistics than seen in previous experiments. The observed mass splittings are not described well by theoretical models, while the relative branching ratios agree with predictions that include relativistic corrections to the radiative transition rates. © 1991 The American Physical Society.
Date: 2013-05-01
Creator: Molly A. Kwiatkowski
Emily R. Gabranski
Kristen E. Huber
M. Christine Chapline
Andrew E., Christie
Patsy S. Dickinson
Access: Open access
- While many neurons are known to contain multiple neurotransmitters, the specific roles played by each co-transmitter within a neuron are often poorly understood. Here, we investigated the roles of the co-transmitters of the pyloric suppressor (PS) neurons, which are located in the stomatogastric nervous system (STNS) of the lobster Homarus americanus. The PS neurons are known to contain histamine; using RT-PCR, we identified a second co-transmitter as the FMRFamide-like peptide crustacean myosuppressin (Crust-MS). The modulatory effects of Crust-MS application on the gastric mill and pyloric patterns, generated in the stomatogastric ganglion (STG), closely resembled those recorded following extracellular PS neuron stimulation. To determine whether histamine plays a role in mediating the effects of the PS neurons in the STG, we bath-applied histamine receptor antagonists to the ganglion. In the presence of the antagonists, the histamine response was blocked, but Crust-MS application and PS stimulation continued to modulate the gastric and pyloric patterns, suggesting that PS effects in the STG are mediated largely by Crust-MS. PS neuron stimulation also excited the oesophageal rhythm, produced in the commissural ganglia (CoGs) of the STNS. Application of histamine, but not Crust-MS, to the CoGs mimicked this effect. Histamine receptor antagonists blocked the ability of both histamine and PS stimulation to excite the oesophageal rhythm, providing strong evidence that the PS neurons use histamine in the CoGs to exert their effects. Overall, our data suggest that the PS neurons differentially utilize their co-transmitters in spatially distinct locations to coordinate the activity of three independent networks. © 2013. Published by The Company of Biologists Ltd.
Date: 2010-01-01
Creator: Elizabeth A. Stemmler
Emily A. Bruns
Christopher R. Cashman
Patsy S. Dickinson
Andrew E., Christie
Access: Open access
- The PISCF-allatostatins (Manduca sexta- or C-type allatostatins) are a family of pentadecapeptides characterized by a pyroglutamine blocked N-terminus, an unamidated-PISCF C-terminus, and a disulfide bridge between two internal Cys residues. Several isoforms of PISCF-AST are known, all from holometabolous insects. Using a combination of transcriptomics and mass spectrometry, we have identified the first PISCF-type peptides from a non-insect species. In silico analysis of crustacean ESTs identified several Litopenaeus vannamei (infraorder Penaeidea) transcripts encoding putative PISCF-AST precursors. Translation of these ESTs, with subsequent prediction of their putative post-translational processing, revealed the existence of as many as three PISCF-type peptides, including pQIRYHQCYFNPISCF (disulfide bridging between Cys7 and Cys14). Although none of the predicted isoforms was detected by mass spectrometry in L. vannamei, MALDI-FTMS mass profiling identified an m/z signal corresponding to pQIRYHQCYFNPISCF (disulfide bridge present) in neural tissue from 28 other decapods, which included members of six infraorders (Stenopodidea, Astacidea, Thalassinidea, Achelata, Anomura and Brachyura). Further characterization of the peptide using SORI-CID and chemical derivatization/enzymatic digestion supported the theorized structure. In both the crab Cancer borealis and the lobster Homarus americanus, MALDI-based tissue surveys suggest that pQIRYHQCYFNPISCF is broadly distributed in the nervous system; it was also detected in the posterior midgut caecum. Collectively, our data show that members of the PISCF-AST family are not restricted to the holometabolous insects, but instead may be broadly conserved within the Pancrustacea. Moreover, our data suggest that one highly conserved PISCF-type peptide, pQIRYHQCYFN-PISCF, is present in decapod crustaceans, functioning as a brain-gut paracrine/hormone. © 2009 Elsevier Inc. All rights reserved.
Date: 2007-07-01
Creator: Patsy S. Dickinson
Jake S. Stevens
Szymon Rus
Henry R. Brennan
Christopher C., Goiney
Christine M. Smith
Lingjun Li
David W. Towle
Andrew E. Christie
Access: Open access
- In arthropods, a group of peptides possessing a -Y(SO3H)GHM/ LRFamide carboxy-terminal motif have been collectively termed the sulfakinins. Sulfakinin isoforms have been identified from numerous insect species. In contrast, members of this peptide family have thus far been isolated from just two crustaceans, the penaeid shrimp Penaeus monodon and Litopenaeus vannamei. Here, we report the identification of a cDNA encoding prepro-sulfakinin from the American lobster Homarus americanus. Two sulfakinin-like sequences were identified within the open-reading frame of the cDNA. Based on modifications predicted by peptide modeling programs, and on homology to the known isoforms of sulfakinin, particularly those from shrimp, the mature H. americanus sulfakinins were hypothesized to be pEFDEY(SO3H)GHMRFamide (Hoa-SK I) and GGGEY(SO3H)DDY(SO3H)GHLRFamide (Hoa-SK II). Hoa-SK I is identical to one of the previously identified shrimp sulfakinins, while Hoa-SK II is a novel isoform. Exogenous application of either synthetic Hoa-SK I or Hoa-SK II to the isolated lobster heart increased both the frequency and amplitude of spontaneous heart contractions. In preparations in which spontaneous contractions were irregular, both peptides increased the regularity of the heartbeat. Our study provides the first molecular characterization of a sulfakinin-encoding cDNA from a crustacean, as well as the first demonstration of bioactivity for native sulfakinins in this group of arthropods.
Date: 2014-12-29
Creator: Kenneth A. Dennison
Thomas W. Baumgarte
Pedro J. Montero
Access: Open access
- We introduce a new time-independent family of analytical coordinate systems for the Kerr spacetime representing rotating black holes. We also propose a (2+1)+1 formalism for the characterization of trumpet geometries. Applying this formalism to our new family of coordinate systems we identify, for the first time, analytical and stationary trumpet slices for general rotating black holes, even for charged black holes in the presence of a cosmological constant. We present results for metric functions in this slicing and analyze the geometry of the rotating trumpet surface.
Date: 2021-02-01
Creator: Ayodeji Ogunnaike
Access: Open access
- While it is well established now that the middle passage did not entirely separate Africans who were forcibly brought to the Americas from their home cultures and traditions, these connections are often studied and understood in the form of survivals or ancestral memory. This paper argues that in major urban centers in Brazil until around the time of World War I, West Africans not only managed to recreate Islamic communities and intellectual traditions, but maintained important contacts with their homelands. In much the same way that scholars have argued that the Sahara constituted an avenue of exchange and connection between North Africa and Bilad al-Sudan, I argue here that the Atlantic Ocean was not an insurmountable barrier but provided opportunities for African Muslims to extend the traditions of Bilad al-Sudan into Brazil—albeit to a much lesser extent.
Date: 2014-12-01
Creator: Nathaniel T Wheelwright
Nalini M Nadkarni
Access: Open access
- La Reserva Biológica Bosque Nuboso Monteverde ha capturado la atención mundial de biólogos, conservacionistas y ecólogos y allí se han hecho vastas investigaciones durante los últimos 40 años. Unos 40.000 ecoturistas visitan el Bosque Nuboso cada año y se considera el bosque lluvioso arquetípico de las altitudes altas. Este libro, una traducción actualizada de "Monteverde: Ecology and Conservation of a Tropical Cloud Forest", editado por Nalini Nadkarni y Nathaniel T. Wheelwright (Oxford University Press, 2000) presenta capítulos sintéticos y recuentos específicos escritos por más de 100 biólogos y residentes locales. En un solo volumen documenta todo lo que se sabe en 2014 de la diversidad biológica de Monteverde, Costa Rica, y cómo protegerla. The Monteverde Cloud Forest Reserve has captured the worldwide attention of biologists, conservationists, and ecologists and has been the setting for extensive investigation over the past 40 years. Roughly 40,000 ecotourists visit the Cloud Forest each year, and it is often considered the archetypal high-altitude rain forest. This book, an updated and expanded version of "Monteverde: Ecology and Conservation of a Tropical Cloud Forest", edited by Nalini Nadkarni and Nathaniel T. Wheelwright (Oxford University Press, 2000), features synthetic chapters and specific accounts written by more than 100 biologists and local residents. The 862-page book includes 12 new short chapters and documents in a single volume everything known in 2014 about the biological diversity of Monteverde, Costa Rica, and how to protect it.
Date: 2024-01-01
Creator: Andrea Rodriguez
Access: Open access
- aeioTU is a Colombian organization that works to enact social change through the field of early childhood education. In collaboration with the Colombian government, aeioTU oversees several public centers located in socioeconomically vulnerable municipalities in Colombia. This thesis analyzes the aeioTU curriculum and the practices of several aeioTU teachers through the theoretical lens of Freire’s critical pedagogy. This thesis argues that by fostering critical awareness of the world from an early age, as well as by collaborating closely with mothers and the communities at large, aeioTU teachers equip children with the tools to become social agents who can challenge and positively change their lived realities. The research presented in this thesis affirms the potential of aeioTU teachers to enact social change in socioeconomically vulnerable communities by building on young children’s social agency.
Date: 2016-11-01
Creator: Robert W. Brown
Stephen G. Naculich
Access: Open access
- Tree-level n-point gauge-theory amplitudes with n − 2k gluons and k pairs of (massless or massive) particles in the fundamental (or other) representation of the gauge group are invariant under a set of symmetries that act as momentum-dependent shifts on the color factors in the cubic decomposition of the amplitude. These symmetries lead to gauge-invariant constraints on the kinematic numerators. They also directly imply the BCJ relations among the Melia-basis primitive amplitudes previously obtained by Johansson and Ochirov.