Showing 1751 - 1760 of 2040 Items

Statement by Rebecca Irving collected by Rachel George on September 11, 2014

Date: 2014-09-11

Creator: Rebecca Irving

Access: Open access



Statement by Anonymous collected by Rachel George on October 14, 2014

Date: 2014-10-14

Creator: Anonymous

Access: Open access



Statement by Anonymous collected by Meredith Eaton on August 5, 2014

Date: 2014-08-05

Creator: Anonymous

Access: Open access



Focus Group Statements

This series includes audio recordings and related transcript of statements by focus groups convened by the TRC. Session participants include Wabanaki foster and adoptive parents, Wabanaki Health and Wellness, Maine-Wabanaki REACH board members, community organizers, and inmates at the Maine Correctional Center. The discussions focus on native fostering and adoption; reconciliation, justice, and trauma; community organization; and background history. Some statement providers requested anonymity, and in those cases, both the transcripts and recordings have been altered to protect participants' identities.

These personal memories provide a window into the realities of the relationship between Wabanaki people and the state of Maine. As evidenced by the recordings themselves, the process of participating in the group discussions was often an emotional one for participants. Readers should be aware that many of the statements contain challenging and disturbing content. The statements are made available online with the hope that broader access to these important historical records will further our understanding of this difficult past and lead to improved child welfare practices for Wabanaki families.

Bowdoin does not hold copyright for these materials. They are made available for research and educational purposes, and with the permission of the TRC and group participants. For all uses outside of "fair use" (as defined by Title 17, United States Code), including derivation, publication, and reproduction, researchers must secure permission from the copyright holders, typically the group participants.

For More Information

If you have questions or concerns about your statement, or if you need research assistance, please contact the George J. Mitchell Department of Special Collections & Archives at scaref@bowdoin.edu or calling 207.725.3288

Visit the website of Wabanaki REACH to stay up to date on the work to implement the Commission’s recommendations. If you participated in the TRC and need support, or if you wish to contribute to the archive by providing a statement, please contact Wabanaki REACH at 207.615.3189

Please also read Wabanaki REACH's statement of support issued upon the release of the archives.

A related series of Statements by Individuals is also available.



Statement gathered at Sipayik-Pleasant Point, Maine, November 13, 2014

Date: 2014-11-13

Creator: Adele Moore

Stephanie Bailey

Garry Moore

Lynn Mitchell

Access: Open access



“Fanny Buitrago: La magia de contar historias”. A Body of One’s Own: Conversations with Caribbean and Latina Writers

Date: 2007-01-01

Creator: Nadia V. Celis Salgado

Fanny Buitrago

Access: Open access



"whimsical contrasts": Love and marriage in The Minister's Wooing and Our Nig

Date: 2011-03-01

Creator: Tess Chakkalakal

Access: Open access



Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases

Date: 2012-09-17

Creator: Takahito Watanabe

Hiroshi Ochiai

Tetsushi Sakuma

Hadley W. Horch

Naoya, Hamaguchi

Taro Nakamura

Tetsuya Bando

Hideyo Ohuchi

Takashi Yamamoto

Sumihare Noji

Taro Mito

Access: Open access

Hemimetabolous, or incompletely metamorphosing, insects are phylogenetically relatively basal and comprise many pests. However, the absence of a sophisticated genetic model system, or targeted gene-manipulation system, has limited research on hemimetabolous species. Here we use zinc-finger nuclease and transcription activator-like effector nuclease technologies to produce genetic knockouts in the hemimetabolous insect Gryllus bimaculatus. Following the microinjection of mRNAs encoding zinc-finger nucleases or transcription activator-like effector nucleases into cricket embryos, targeting of a transgene or endogenous gene results in sequence-specific mutations. Up to 48% of founder animals transmit disrupted gene alleles after zinc-finger nucleases microinjection compared with 17% after microinjection of transcription activator-like effector nucleases. Heterozygous offspring is selected using mutation detection assays that use a Surveyor (Cel-I) nuclease, and subsequent sibling crosses create homozygous knockout crickets. This approach is independent from a mutant phenotype or the genetic tractability of the organism of interest and can potentially be applied to manage insect pests using a non-transgenic strategy. © 2012 Macmillan Publishers Limited. All rights reserved.



Messenger RNA transport in the opportunistic fungal pathogen Candida albicans

Date: 2017-12-01

Creator: Anne E. McBride

Access: Open access

Candida albicans, a common commensal fungus, can cause disease in immunocompromised hosts ranging from mild mucosal infections to severe bloodstream infections with high mortality rates. The ability of C. albicans cells to switch between a budding yeast form and an elongated hyphal form is linked to pathogenicity in animal models. Hyphal-specific proteins such as cell-surface adhesins and secreted hydrolases facilitate tissue invasion and host cell damage, but the specific mechanisms leading to asymmetric protein localization in hyphae remain poorly understood. In many eukaryotes, directional cytoplasmic transport of messenger RNAs that encode asymmetrically localized proteins allows efficient local translation at the site of protein function. Over the past two decades, detailed mechanisms for polarized mRNA transport have been elucidated in the budding yeast Saccharomyces cerevisiae and the filamentous fungus Ustilago maydis. This review highlights recent studies of RNA-binding proteins in C. albicans that have revealed intriguing similarities to and differences from known fungal mRNA transport systems. I also discuss outstanding questions that will need to be answered to reach an in-depth understanding of C. albicans mRNA transport mechanisms and the roles of asymmetric mRNA localization in polarized growth, hyphal function, and virulence of this opportunistic pathogen.