Showing 1011 - 1020 of 2039 Items
Date: 2010-01-13
Creator: Sean Cleary
Murray Elder
Andrew Rechnitzer
Jennifer Taback
Access: Open access
- We consider random subgroups of Thompson's group F with respect to two natural stratifications of the set of all k-generator subgroups. We find that the isomorphism classes of subgroups which occur with positive density are not the same for the two stratifications. We give the first known examples of persistent subgroups, whose isomorphism classes occur with positive density within the set of k-generator subgroups, for all sufficiently large k. Additionally, Thompson's group provides the first example of a group without a generic isomorphism class of subgroup. Elements of F are represented uniquely by reduced pairs of finite rooted binary trees. We compute the asymptotic growth rate and a generating function for the number of reduced pairs of trees, which we show is D-finite (short for differentiably finite) and not algebraic. We then use the asymptotic growth to prove our density results. © European Mathematical Society.
Date: 1998-04-01
Creator: Zheng Hui He
Deze He
Bruce D. Kohorn
Access: Open access
- Pathogen infection of angiosperms must rely on some interaction between the extracellular matrix (ECM) and the invading agent, and may be accompanied by signaling between the ECM and cytoplasm. An Arabidopsis cell wall associated receptor kinase (Wak1) has an amino-terminal domain that is tightly associated with the ECM, spans the plasma membrane and has a cytoplasmic protein kinase domain. Wak1 expression is induced when Arabidopsis plants are infected with pathogen, or when the pathogen response is stimulated either by exogenous salicylate (SA) or its analog 2,2-dichloroisonicotinic acid (INA). This Wak1 induction requires the positive regulator NPR1/NIM1. Thus Wak1 is a pathogen-related (PR) protein. Expression of an antisense and a dominant negative allele of Wak1 shows that induced expression of Wak1 is needed for a plant to survive if stimulated by INA. Ectopic expression of the entire Wak1, or the kinase domain alone, can provide resistance to otherwise lethal SA levels. These experiments suggest that Wak1 expression and other PR proteins are protecting plants from detrimental effects incurred during the pathogen response. These results provide a direct link between a protein kinase that could mediate signals from the ECM, to the events that are precipitated by a pathogen infection.
Date: 1986-01-01
Creator: P. R. Chitnis
E. Harel
B. D. Kohorn
E. M. Tobin
J. P., Thornber
Access: Open access
- When the in vitro synthesized precursor of a light-harvesting chlorophyll a/b binding protein (LHCP) from Lemna gibba is imported into barley etiochloroplasts, it is processed to a single form. Both the processed form and the precursor are found in the thylakoid membranes, assembled into the light-harvesting complex of photosystem II. Neither form can be detected in the stromal fraction. The relative amounts of precursor and processed forms observed in the thylakoids are dependent on the developmental stage of the plastids used for uptake. The precursor as well as the processed form can also be detected in thylakoids of greening maize plastids used in similar uptake experiments. This detection of a precursor in the thylakoids, which has not been previously reported, could be a result of using rapidly developing plastids and/or using an heterologous system. Our results demonstrate that the extent of processing of LHCP precursor is not a prerequisite for its inclusion in the complex. They are also consistent with the possibility that the processing step can occur after insertion of the protein into the thylakoid membrane.
Date: 2017-12-01
Creator: Alia Hamieh
Naomi Tanabe
Access: Open access
- In this paper, we prove that a primitive Hilbert cusp form g is uniquely determined by the central values of the Rankin-Selberg L-functions (formula presented), where f runs through all primitive Hilbert cusp forms of level q for infinitely many prime ideals q. This result is a generalization of the work of Luo (1999) to the setting of totally real number fields.
Date: 1982-01-01
Creator: B. D. Kohorn
P. M.M. Rae
Access: Open access
- An extract of Drosophila melanogaster Kc cells is shown to give specific and accurate transcription of truncated segments of cloned D. melanogaster ribosomal DNA (rDNA). When clones are digested with restriction enzymes so that the initiation site is flanked by 0.3 kilobase (kb) of nontranscribed spacer and >0.4 kb of external transcribed spacer, RNA polymerase I activity in the extract parallels in vivo rRNA synthesis in selection of the coding strand of template and the site of transcription initiation. When >0.3 kb of the nontranscribed spacer is contiguous with transcribed spacer, in vitro initiations evidently also occur in repeated sequences adjacent to the site of in vivo initiation; when ≤0.4 kb of the external transcribed spacer is present in a segment, expected transcripts are heterogeneous in length or not detectable. Transcription in the cell-free system requires the specific addition of D. melanogaster rDNA: neither D. virilis rDNA, vector plasmid, nor clones of D. melanogaster genes that are transcribed in vivo by RNA polymerases II and III serve as templates in the system. Drosophila rDNA units that have an interruption in the 28S rRNA coding region are not transcribed in vivo, but restriction digests of a recombinant phage DNA that contains such a unit are active as template for in vitro rDNA transcription.
Date: 2018-09-07
Creator: Alan Hastings
Karen C. Abbott
Kim Cuddington
Tessa Francis
Gabriel, Gellner
Ying Cheng Lai
Access: Open access
- The importance of transient dynamics in ecological systems and in the models that describe them has become increasingly recognized. However, previous work has typically treated each instance of these dynamics separately. We review both empirical examples and model systems, and outline a classification of transient dynamics based on ideas and concepts from dynamical systems theory. This classification provides ways to understand the likelihood of transients for particular systems, and to guide investigations to determine the timing of sudden switches in dynamics and other characteristics of transients. Implications for both management and underlying ecological theories emerge.
Date: 1993-01-01
Creator: Stephen G. Naculich
Access: Open access
- Relations among fermion masses and mixing angles at the scale of grand unification are modified at lower energies by renormalization group running induced by gauge and Yukawa couplings. In super-symmetric theories, the b quark and lepton Yukawa couplings, as well as the t quark coupling, may cause significant running if tan, the ratio of Higgs field expectation values, is large. We present approximate analytic expressions for the scaling factors for fermion masses and CKM matrix elements induced by all three third generation Yukawa couplings. We then determine how running caused by the third generation of fermions affects the predictions arising from three possible forms for the Yukawa coupling matrices at the GUT scale: the Georgi-Jarlskog, Giudice, and Fritzsch textures. © 1993 The American Physical Society.
Date: 2015-03-25
Creator: Travis N. Ridout
Michael M. Franz
Erika Franklin Fowler
Access: Open access
- This research examines how an attack ad’s sponsorship conditions its effectiveness. We use data from a survey experiment that exposed participants to a fictional campaign ad. Treatments varied the ad’s sponsor (candidate vs. group), the group’s donor base (small donor vs. large donors), and the format of the donor disclosure (news reports vs. disclaimers in the ads). We find that ads sponsored by unknown groups are more effective than candidate-sponsored ads, but disclosure of donors reduces the influence of group advertising, leveling the playing field such that candidate- and group-sponsored attacks become equally effective. Increased disclosure does not, however, advantage small-donor groups over large-donor groups.
Date: 2019-05-01
Creator: Anja Forche
Norma V. Solis
Marc Swidergall
Robert Thomas
Alison, Guyer
Annette Beach
Gareth A. Cromie
Giang T. Le
Emily Lowell
Norman Pavelka
Judith Berman
Aimeé M. Dudley
Anna Selmecki
Scott G. Filler
Access: Open access
- When the fungus Candida albicans proliferates in the oropharyngeal cavity during experimental oropharyngeal candidiasis (OPC), it undergoes large-scale genome changes at a much higher frequency than when it grows in vitro. Previously, we identified a specific whole chromosome amplification, trisomy of Chr6 (Chr6x3), that was highly overrepresented among strains recovered from the tongues of mice with OPC. To determine the functional significance of this trisomy, we assessed the virulence of two Chr6 trisomic strains and a Chr5 trisomic strain in the mouse model of OPC. We also analyzed the expression of virulence-associated traits in vitro. All three trisomic strains exhibited characteristics of a commensal during OPC in mice. They achieved the same oral fungal burden as the diploid progenitor strain but caused significantly less weight loss and elicited a significantly lower inflammatory host response. In vitro, all three trisomic strains had reduced capacity to adhere to and invade oral epithelial cells and increased susceptibility to neutrophil killing. Whole genome sequencing of pre- and post-infection isolates found that the trisomies were usually maintained. Most post-infection isolates also contained de novo point mutations, but these were not conserved. While in vitro growth assays did not reveal phenotypes specific to de novo point mutations, they did reveal novel phenotypes specific to each lineage. These data reveal that during OPC, clones that are trisomic for Chr5 or Chr6 are selected and they facilitate a commensal-like phenotype.
Date: 2009-09-01
Creator: Rebecca Teed
Charles Umbanhower
Philip Camill
Access: Open access
- Aspen parkland in central Canada may change substantially with increased warming and aridity as prairies replace forests, fire return intervals decrease and lake levels decline. We examined the relationships among vegetation, climate, fire and lake-ecosystem properties using lake sediment cores from the current northern and southern boundaries of the aspen parkland in southwestern Manitoba. We analyzed pollen, charcoal, sediment magnetics, biogenic silica, phosphorus, grain size and LOI, and dated the cores using Pb and C (AMS, calibrated). The Jones Lake record, from the southern edge of the parkland, began considerably earlier (~11 000 cal. BP) than the Mallard Pond record at the northern edge (~8600 cal. BP). These sites were characterized as prairie communities with low fire severity and relatively low lake productivity during the warm, dry period from 9000 to 6000 cal. BP. Beginning around 6500 cal. BP at Jones Lake and 3400 cal. BP at Mallard Pond, conditions appeared to get wetter as indicated by arboreal pollen percentage increases from ~30% to 40-60%, concurrent with a rise in charcoal and proxies for lake productivity (biogenic silica and percent organic phosphorus). Similar to previous studies along the prairie-forest border, we found that charcoal increased during warmer, wetter periods with increased forest cover and fuel loading rather than during warmer, drier periods of prairie dominance. Our results underscore the importance of regional changes in moisture, and its effects on lake levels and forest biomass, as a dominant control of the aspen parkland dynamics. © The Author(s), 2009. 210 14