Honors Projects
Showing 91 - 100 of 564 Items
Antimicrobial Compounds in the Lobster, Homarus americanus: An Investigation of Lobster Shell Extracts This record is embargoed.
- Embargo End Date: 2027-05-19
Date: 2022-01-01
Creator: Usira Ahmed Ali
Access: Embargoed
“Unstuck in Time and Space”: Time Travels in Teen Cinema Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2021-01-01
Creator: Hallowell Lyne
Access: Access restricted to the Bowdoin Community
Chromatin-conformation differences in natural populations of D. melanogaster Access to this record is restricted to members of the Bowdoin community. Log in here to view.
- Restriction End Date: 2026-06-01
Date: 2021-01-01
Creator: Nicholas J. Purchase
Access: Access restricted to the Bowdoin Community
The Photocatalytic Degradation of Ibuprofen and Atenolol Using Bismuth Oxychloride and Titanium Dioxide
Date: 2021-01-01
Creator: Kamyron Anthony Speller
Access: Open access
- Pharmaceuticals and personal care products (PPCPs) are contaminating natural bodies of water and are problematic for aquatic organisms and ecosystems. Generally, PPCPs are introduced to water systems due to incomplete removal by wastewater treatment plants (WWTPs). As such, it is vital to find ways to remediate these problematic contaminants before they are discharged into the environment. In this study, two photocatalysts¾titanium dioxide (TiO2) and bismuth oxychloride (BiOCl)¾were compared to determine their relative efficiencies (degradation rates) and dominant degradation mechanism (hydroxyl radical production or direct oxidation) with the goal of photocatalytically degrading two pharmaceuticals, atenolol and ibuprofen, using UV (254 nm) light. While TiO2 has been used extensively for photocatalytic degradation, BiOCl is a newer photocatalyst. The two pharmaceuticals selected for study represent two large classes of drugs (aryloxypropanolamine and propionic acid derivatives, respectively) that have been detected in the influent into and effluent from wastewater treatment plants and in the environment. When irradiated at 254 nm, BiOCl degrades ibuprofen with a rate constant 15 times greater than TiO2. On the other hand, TiO2 degrades atenolol with a rate constant 2.2 times greater than BiOCl. LCMS analysis of photodegradation products reveals different products produced by the two photocatalysts, providing evidence for the dominance of different degradation mechanisms for the two photocatalysts. In summary, this work suggests that BiOCl, potentially used in combination with TiO2, holds potential for degrading PPCPs in natural bodies of water.
Palimpsestuous London: Spatial and Temporal Layering in Fin-de-Siècle Victorian Fiction Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2015-05-01
Creator: Elisabeth A Strayer
Access: Access restricted to the Bowdoin Community
Semaphorin-Induced Plasticity in the Nervous System of the Cricket, Gryllus bimaculatus
Date: 2021-01-01
Creator: Alicia G. Edwards
Access: Open access
- The adult auditory system of the cricket, Gryllus bimaculatus, exhibits a rare example of neuronal plasticity. Upon deafferentation, we observe medial dendrites that normally respect the midline of the PTG in the central nervous system sprouting across the boundary and forming synaptic connections with the contralateral auditory afferents. The Horch Lab has investigated key molecular factors that might play a causal role in this paradigm. Specifically, the protein Sema1a.2 comes from a guidance molecule family and has a role in developmental neuronal plasticity in other organisms. In this study, I explored the role of Sema1a.2 in the neuronal plasticity of the adult auditory system of the cricket by conducting a series of dsRNA knockdown experiments targeting Sema1a.2 followed by backfill procedures in which we iontophoresed dye into the Ascending Neurons (ANs) to visualize the anatomical effects of the knockdown experiments using confocal microscopy. We found that there were no significant differences between animals injected with dsRNA against GFP and Sema1a.2 volume, with respect to qualitative and quantitative data. However, we believe with an increase in cohort size, the trends observed, particularly the effect of Sema1a.2 knockdowns on CWM and CBM volumes, will become more pronounced and significant. Potential future pathways could include conducting double knockdowns of Sema1a.2 and Sema2a to observe if these two proteins are working together to create a more obvious effect on midline crossing and branching. Other options also include looking into other protein families that might be the causing factor in this rare phenomenon (toll-like receptors).
Characterization of Yellow Family Proteins in Gryllus bimaculatus
Date: 2021-01-01
Creator: Alexandra W. Rubenstein
Access: Open access
- Neuronal plasticity occurs in developing nervous systems, with adult organisms rarely able to recover from neurological damage. The cricket, Gryllus bimaculatus, is useful to study neuronal plasticity due to its reorganization of the auditory system in response to injury beyond development. When a cricket ear is removed and auditory afferents severed, a rare phenomenon occurs: the dendrites of interneurons on the deafferented side cross the typically-respected midline of the prothoracic ganglion to form functional synapses with auditory afferents from the opposite side. To find proteins involved in this phenomenon, the Horch Lab assembled a de novo transcriptome from neurons in the prothoracic ganglion of G. bimaculatus. Differential gene expression analysis revealed upregulated protein yellows post-deafferentation, indicating these proteins could influence neuronal plasticity in the adult cricket CNS. I focused on characterizing the protein yellow family in the cricket. By relating protein yellows evolutionarily, mapping them onto the genome, and analyzing their sequences, I discovered the cricket has 10 yellow genes, including a newly identified yellow-r* and a block of yellows showing synteny with insect genomes. Additionally, yellow-e and -x in crickets are closely related to bacterial yellow, perhaps indicating a role for horizontal gene transfer in yellow gene evolution. The protein upregulated in the cricket CNS is closely related with yellow-f’s in other insects, indicating yellow-f is likely a secreted protein, highly expressed in the CNS, multifunctional, and conserved across insects. Characterizing yellow-f can give insight into how these upregulated proteins might be related to neuronal plasticity in G. bimaculatus.
Jigs, Reels, and “Realness”: An Investigation of Ideas of Authenticity and Tradition in New England French Canadian Music
Date: 2021-01-01
Creator: Lowell Ruck
Access: Open access
- Franco-American culture is increasingly recognized as an integral part of the heritage of Maine and New England, and has attracted growing academic attention in recent years. But while many scholars and cultural promoters focus on the French language in their work on this subject, few studies have considered the position of traditional music in Franco-American communities in the 21st century. This thesis examines French Canadian traditional music as it is played in New England and the ways in which musicians think about authenticity and tradition in their art. Using material from ethnographic interviews, it illuminates how musicians draw from individual, familial, and communal experiences and from past, present, and future conceptions of authentic tradition in their roles as cultural mediators. Ultimately, it suggests that players of French Canadian traditional music interact with this tradition in diverse ways, and that in doing so, they help to maintain the vibrancy of Franco-American cultural practices. La culture franco-américaine est reconnue de plus en plus comme partie intégrante de l’héritage du Maine et de la Nouvelle-Angleterre et attire maintenant l’attention académique. Mais même si beaucoup d’érudits et de promoteurs culturels ciblent la langue française dans leur travail sur ce sujet, peu d’études ont considéré la position de la musique traditionnelle dans les communautés franco-américaines du XXIe siècle. Cette thèse se concentre sur la musique traditionnelle canadienne-française de la Nouvelle-Angleterre et sur les façons dont les musiciens conceptualisent l’authenticité et la tradition dans leur art. En utilisant des entrevues ethnographiques, elle illumine comment les musiciens tirent des expériences individuelles, familiales et communautaires et des idées du passé, du présent et de l’avenir dans leurs rôles comme médiateurs culturels. Finalement, elle suggère que les joueurs de la musique traditionnelle canadienne-française interagissent avec cette tradition de plusieurs façons, et ce faisant, aident à maintenir la brillance des pratiques culturelles franco-américaines.
Possessing Her: Embodying Identity in Exorcism Cinema Access to this record is restricted to members of the Bowdoin community. Log in here to view.
Date: 2021-01-01
Creator: Alicia Echavarria
Access: Access restricted to the Bowdoin Community
Critical Phenomena in the Gravitational Collapse of Electromagnetic Dipole and Quadrupole Waves
Date: 2021-01-01
Creator: Maria F. Perez Mendoza
Access: Open access
- We report on critical phenomena in the gravitational collapse of electromagnetic waves. Generalizing earlier results that focused on dipole electromagnetic waves, we here compare with quadrupole waves in axisymmetry. We perform numerical simulations of dipole and quadrupole wave initial data, fine-tuning both sets of data to the onset of black hole formation in order to study the critical solution and related critical phenomena. We observe that different multipole moments have different symmetries, indicating that the critical solution for electromagnetic waves cannot be unique, at least not globally. This is confirmed in our numerical simulations: while dipole data lead to a single center of collapse, at the center of symmetry, quadrupole data feature two separate centers of collapse on the symmetry axis, above and below the center of symmetry -- reminiscent of similar findings reported for critical collapse of vacuum gravitational waves. While the critical solution for neither the dipole nor the quadrupole data is exactly self-similar, we find that their approximate echoing periods appear to differ, as do the critical exponents. We discuss whether the centers of collapse found for dipole and quadrupole data might all have the same properties, which would suggest a ``local uniqueness" of the critical solution. Instead, we provide some evidence -- including the differing echoing periods and critical exponents -- suggesting that the critical solutions are distinct even locally. We speculate on the implications of our findings for critical phenomena in the collapse of vacuum gravitational waves, which share with electromagnetic waves the absence of a spherically symmetric critical solution.