Honors Projects
Showing 221 - 230 of 564 Items
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Responses of central pattern generators in the American lobster STNS to multiple members of a novel neuropeptide family
- Neuropeptides are important modulators of neural activity, allowing neural networks, such as the central pattern generators (CPGs) that control rhythmic movements, to alter their output and thus generate behavioral flexibility. Isoforms of a neuropeptide family vary in physical structure, allowing potentially distinct functional neuromodulatory effects on CPG systems. While some familial neuropeptide isoforms can differentially affect a system, others in the same family may elicit indistinguishable effects. Here, we examined the effects elicited by members of a novel family of six peptide hormone isoforms (GSEFLamides: I-, M-, AL-, AM-, AV-, and VM-GSEFLamide) on the pyloric filter and gastric mill CPGs in the stomatogastric nervous system (STNS) of the American lobster, Homarus americanus. Recent unpublished work from the Dickinson lab found that five of the six GSEFLamides elicited similar increases in contraction amplitude when perfused through the isolated lobster heart, while one (AVGSEFLamide) had virtually no effect. Using extracellular recordings, we found the pattern of GSEFLamide effects on the STNS gastric mill to be similar to the pattern observed in the lobster cardiac system; the gastric mill circuit was fairly consistently activated by all isoforms except AVGSEFLamide. The intrinsically active pyloric pattern was also significantly enhanced by three out of five peptide isoforms, and nearly significantly enhanced by two more, but was likewise non-responsive to AVGSEFLamide. While the reason AVGSEFLamide had no effect on either pattern is unknown, the similar phenomenon noted in the isolated whole heart potentially indicates that this isoform lacks any function in the lobster.
2020

That’s DOPE: the delayed-onset, prolonged excitation response of a primary auditory interneuron in Gryllus bimaculatus
2020
Survival Strategies: Historic Preservation, Jewish Community, and the German Democratic Republic
- Following the Second World War, as German Communists worked to establish a new socialist East German state, Jews who survived persecution and imprisonment by the Nazis worked to reestablish a Jewish community at the same time. Though many scholars dismiss the relationship between Jews and the Socialist Unity Party, the ruling party of the German Democratic Republic, as one characterized only by neglect and occasional political exploitation, it was much more nuanced, shaped in large part by the Cold War. Both the party and the Jewish community relied on the other to accomplish their goals, namely, survival in a new world order: The Socialist Unity Party relied on the Jewish community to maintain the German Democratic Republic's claim to legitimacy, and the Jews, few in number, relied on the party for financial support. Despite mutual benefits, however, the state and party nearly always had the upper hand. The power imbalance led Jews to find creative ways to fulfill their needs and, at several points, even prompted protest of the party’s treatment of its Jewish citizens. This paper follows the course of this relationship by focusing on the German Democratic Republic's management of sites of historical significance—which vacillated between outright destruction and dedicated protection—returning particularly to the Jewish cemetery in Berlin-Weissensee, one of the largest Jewish cemeteries in Europe. With this particular lens, this project addresses questions about memory, mythology, and agency in a socialist dictatorship and challenges assumptions about Jewish life in East Germany.
2020

Food Comes First: Growing Up at my Family’s Table
2020
Perdido en la transculturación: Compromisos de identidad en la América Latina judía
- Esta investigación explora los procesos de negociación y compromiso presentes en la experiencia judía de América Latina. Durante siglos, esta identidad ha existido junta con otras, sean nacionales, religiosas, o raciales, lo cual resulta en una nueva identidad compleja y singular. A través de novelas de Eduardo Halfon (Guatemala), Achy Obejas y Leonardo Padura (Cuba) e Isaac Goldemberg (Perú) en adición a una investigación antropológica en Lima, el texto explora una colección de temas que incluye el movimiento, la memoria, el exilio, la diáspora, el trauma, y el mestizaje. Cada tema aquí analizado tiene un rol profundo en la formación de la identidad judía de América Latina, tanto en su forma histórica como en su forma actual.
2020

The Photodegradation of Endocrine Disrupting Compounds in Aqueous Solutions
2014
Bubbles & Bought-Ins: Reevaluating Price Movements in the Art Market
- Employs two tests for bubbles in the art market. First, a right-hand forward recursive augmented Dickey-Fuller test to identify explosive price movements. Second, a test for the statistical significance of hedonic regression price index coefficients after controlling for equity market performance. Finds strong evidence for a speculative bubble in the pre-Great Recession "Post-War & Contemporary" market. Evidence for this bubble diminishes but does not dissipate after accounting for the effect of failed sales on index returns.
2020

Gateway to the Forest City? Portland, Maine's Bayside Neighborhood, 1866-2014
2014

Functionality of Candida albicans She3 in the mRNA transport of Saccharomyces cerevisiae
2021
A Moderated-Mediation Model of Emerging Adult and Parent Religiosity, Externalizing Behavior, and Parenting Style
- The present study investigated whether emerging adult religiosity mediated the relationship between high parental religiosity and low levels of offspring externalizing, and whether these pathways are moderated by aspects of authoritative parenting (i.e., acceptance, firm control, and psychological autonomy). Surveys were completed by 275 emerging adults aged 18-25, including scales assessing their religiosity, the religiosity of their parents, the style of parenting in which they were raised, and their own engagement in externalizing behaviors. Results indicated a correlation between high levels of parental and emerging adult religiosity, and a marginal relationship between high parental religiosity and reduced offspring externalizing. However, emerging adult religiosity was not related to externalizing, such that no mediation model could be tested. Psychological autonomy granting moderated the relationship between parental religiosity and emerging adult externalizing: low parental religiosity was associated with high levels of emerging adult externalizing only in parents who exhibited low levels of psychological autonomy granting, while high parental religiosity was related to low emerging adult externalizing regardless of psychological autonomy granting. The results indicate a complex relationship between parenting, externalizing, and religiosity.
2021